Theanine as an adjuvant therapy for chronic schizophrenia
Phase 2
- Conditions
- Schizophrenia.Schizophrenia
- Registration Number
- IRCT20090117001556N133
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Diagnosis of schizophrenia based on DSM-5.
Minimum score of 60 based on PANSS.
Age range: 18-55 years.
At least, 2 years have passed since the onset of the disorder.
Exclusion Criteria
Diagnosis of another disorder in axis II.
Existence of a significant neurological or organic disease.
IQ less than 70 based on interviewer clinical suspicion.
Substance/drug dependence during the last 6 months (except nicotine and caffeine).
Use of antipsychotics during past 1 week or long-term antipsychotics during past 1 month.
Receiving ECT during the last 2 weeks.
Abnormal endocrine activity.
Abnormal kidney and liver function.
History of trombosis and embolia.
History of abnormal bleeding.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of schizophrenia. Timepoint: Baseline and weeks 4 and 8. Method of measurement: By Positive and Negative Syndrome Scale (PANSS).
- Secondary Outcome Measures
Name Time Method