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Examining the Effectiveness of Transdiagnostic, Internet-Delivered Cognitive Behaviour Therapy in New Mothers Experiencing Anxiety and Depression

Not Applicable
Completed
Conditions
Anxiety
Depression, Postpartum
Interventions
Behavioral: Therapist-assisted ICBT
Registration Number
NCT04012580
Lead Sponsor
University of Regina
Brief Summary

In the proposed study, the investigators will examine the efficacy of transdiagnostic, Internet-delivered cognitive behaviour therapy (ICBT) in the treatment of postpartum anxiety and depression. Half of participants will receive the treatment immediately, and half of the participants will be assigned to a treatment-as-usual control condition. Participants assigned to the control condition will be offered the treatment after a 12-week waiting period, although data from this portion will not be included in the current study. All participants will complete questionnaires prior to the start of the treatment, following treatment (or corresponding 8-week waiting period), at 1-months follow-up (or corresponding 12-week waiting period), and at 6-months follow-up (in those assigned to the treatment condition). Further, those who receive the treatment will complete questionnaires on a weekly basis. The primary outcome measures include anxiety and depression. As part of the battery of questionnaires administered after the completion of the program, participants will be asked to rate the program content, the overall service, and their satisfaction with the program.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
60
Inclusion Criteria
  • 18 years of age or older
  • female
  • have given birth and have a child under one year of age
  • score of 10 or above on EPDS or a score of 9 or above on the GAD-7
  • be a resident of Saskatchewan
  • have access to a secure computer and the Internet, and be comfortable using technology
  • be available to work through treatment each week
  • be willing to provide a medical contact as an emergency contact
Exclusion Criteria
  • younger than 18 years
  • not female
  • have not given birth to a child less than one year of age
  • are experiencing minimal to no symptoms of anxiety and/or depression
  • are not a resident of Saskatchewan
  • have been hospitalized within the last year for mental health and/or suicide risk concerns;
  • have unmanaged problems with alcohol, drugs, psychosis or mania, or are at increased suicide risk (specific plans and intent reflected by the Suicide Behaviors Questionnaire-Revised)
  • started a new psychotropic medication within the past month
  • do not have access to a secure computer and the Internet or is not comfortable using technology
  • are not available to work through treatment each week
  • are not willing to provide a medical contact as an emergency contact

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Therapist-assisted ICBTTherapist-assisted ICBTAn 8-week transdiagnostic internet-delivered cognitive behavioural therapy (ICBT) will be delivered to participants. In addition to the program, participants will receive support from registered social workers, psychologists or supervised graduate students, with experience delivering ICBT, with contact provided on a weekly basis.
Primary Outcome Measures
NameTimeMethod
Change in postpartum depressionBaseline, weeks 1-9, 13, and 37

Measured by the Edinburgh Postnatal Depression Scale (EPDS). 10 items are summed into a total score ranging from 0 to 30, with higher scores indicating more severe depression.

Change in anxietyBaseline, weeks 1-9, 13, and 37

Measured by the Generalized Anxiety Disorder Scale 7-Item (GAD-7). 7 items are summed into a total score ranging from 0 to 21, with higher scores indicating more severe self-reported levels of anxiety.

Secondary Outcome Measures
NameTimeMethod
Service utilizationWeeks 9, 13, and 37

Measured by a series of questions asking participants whether they accessed additional services or support

Change in depressionBaseline, weeks 1-9, 13, and 37

Measured by the Patient Health Questionnaire 9-Item (PHQ-9). 9 items are summed into a total score, with scores ranging from 0 to 27. Higher scores are associated with higher depression severity.

Change in depression, anxiety, stressBaseline, 8 weeks, 1 month, and 6 months

Measured by the Depression and Anxiety Stress Scales (DASS-21). 21 items are summed into a total score ranging from 0 to 42, with higher scores indicating more severe symptoms with respect to the depression, anxiety, and stress subscales.

Mother-infant bondingBaseline, weeks 9, 13, and 37

Measured by the Postnatal Bonding Questionnaire (PBQ). 25 items are summed into a total score ranging from 0 to 125, with higher scores indicating more reported difficulties bonding with one's baby.

Relationship satisfactionBaseline, weeks 9, 13, and 37

Measured by the Dyadic Adjustment Scale-7 item (DAS-7). 7 items are summed into a total score ranging from 0 to 32, with higher scores indicating greater perceived relationship quality.

Treatment credibilityBaseline and week 9

Measured by the Credibility/Expectancy Questionnaire (CEQ). 6 items are summed into a total score and two subscales (credibility and expectancy). Total scores can range from 3 to 27, with higher scores representing greater perceptions of ICBT credibility.

Therapeutic alliance9 weeks following baseline

Measured by the Working Alliance Inventory-Short Revised (WAI-SR). Scores are summed into three sub-total scores, which respectively assess various domains of the therapeutic relationship (i.e., goal, task, and bond). Sub-total scores each range between 5 and 20, with higher scores representing better therapeutic relationship in each of the three domains assessed.

Treatment satisfaction9 weeks following baseline

Measured by the Treatment Satisfaction Questionnaire (TSQ). 6 items are scored using various scales. Descriptive statistics are produced for each item.

Adverse effects9 weeks following baseline

Measured by questions assessing whether participants encountered any adverse effects of treatment, developed any new psychological symptoms, or experienced any unexpected events over the course of treatment

Trial Locations

Locations (1)

Online Therapy Unit, University of Regina

🇨🇦

Regina, Saskatchewan, Canada

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