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A Phase II Clinical Trial of Carbon-ion Radiotherapy for Locally Advanced Pancreatic Cancer

Phase 2
Conditions
ocally Advanced Pancreatic Cancer
Registration Number
JPRN-UMIN000030762
Lead Sponsor
Kanagawa Cancer Center, Kanagawa Prefectural Hospital Organization
Brief Summary

This study confirmed safety and efficacy comparable to those reported from prior facilities.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Not provided

Exclusion Criteria

1) Patient with direct invasion in the gastrointestinal tract which fulfills either following conditions; (a) Endoscopic findings of obvious invasion in stomach and duodenum (b) Imaging findings, including those by computed tomography, of invasion inside the gastrointestinal tract 2) Obvious peritoneal dissemination, except for small amount of ascites or negative cytology of ascites 3) Gastric or duodenal ulcer, except for ulcer scar 4) Metallic stent for occlusive jaundice 5) Open injury or active and intractable infection in the target lesion 6) Severe complications such as severe cerebrovascular disease, intractable diabetes, severe cardiovascular disease, angina, myocardial infarction within 3 months from the onset, severe liver dysfunction, severe psychiatric disease if concomitant radiochemotherapy is selected, Severe complication which influences irradiation of carbon-ion beam such as psychiatric disease if carbon-ion radiotherapy alone is selected 7) Active and untreated double cancer, except for intraepithelial carcinoma, intramucinous carcinoma or malignancy controlled for a long-term 8) Medically or psychologically unsuitable conditions

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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