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临床试验/NCT06813092
NCT06813092已完成不适用

Effects of a Single Bout of High Intensity, High Velocity Resistance Exercise Compared to Whole-body Electromyostimulation on Cardiometabolic Risk Factors and Markers of Bone Formation and -Resorption in Young Female Dentists.

University of Erlangen-Nürnberg Medical School2 个研究点 分布在 1 个国家目标入组 16 人开始时间: 2025年3月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
16
试验地点
2
主要终点
Changes for C-terminal telopeptide of type I collagen from pre- to 15 min post-exercise

研究概览

简要总结

Due to their high workload and unfavorable working position, young female dentists are particularly at risk of cardiometabolic diseases and an early reduction in bone mineral density (BMD). With focus on the latter issue, short bouts of resistance exercise with high strain magnitude and velocity are commonly considered to be a feasible option to prevent bone loss in the early years of young adulthood. In parallel, whole-body electromyostimulation (WB-EMS) a trainings technology able address all main muscle groups simultaneously, however with dedicated exercise intensity might be a time-effective, joint friendly and safe option to maintain BMD in people unable or unmotivated to exercise conventionally. In the present study, we aim to compare the effects of a single session of WB-EMS versus high intensity, high velocity resistance exercise on biomarkers of bone formation (Procollagen type 1 N propeptide, P1NP) and resorption (C-terminal telopeptide of type I collagen, CTX-I). We hypothesize that no clinically relevant different effects on P1NP and CTX-I were determined.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Single (Outcomes Assessor)

盲法说明

Outcome assessor were not aware of the group status and were not allowed to ask correspondingly

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Female
接受健康志愿者
否

入选标准

  • •female dental students (>3rd semester) or licensed dentists
  • •no competitive sports background for >2 years
  • •normal body mass (BMI>18,5 and <25 kg/m2)

排除标准

  • •more than one resistance exercise session per week (last 12 month)
  • •whole-body electromyostimulation during the last 12 month
  • •amenorrhea, oligomenorrhea

研究组 & 干预措施

Whole-Body Electromyostimulation

Experimental

One single bout of whole-body electromyostimulation (20 min, bipolar, 85 Hz, 350 µs, rectangular, 6s of impulse, 4s of rest)

干预措施: Whole-Body Electromyostimulation (Other)

Resistance exercise

Active Comparator

High intensity, high velocity resistance exercise (30 min, 5-6 exercises, 3 sets at 60-85% 1RM)

干预措施: Resistance exercise (Other)

结局指标

主要结局

Changes for C-terminal telopeptide of type I collagen from pre- to 15 min post-exercise

时间窗: Immediately pre-exercise to 15 min post exercise of a single exercise session

Changes for C-terminal telopeptide of type I collagen (CTX-I) serum levels from pre- to 15 min post-exercise as determined by blood samples

次要结局

  • Changes for hemoglobin A1c from pre- to 15 min post-exercise(Immediately pre- to 15 min post-exercise of a single exercise session)
  • Changes for Procollagen type 1 N propeptide from pre- to 15 min post-exercise(Immediately pre-exercise to 15 min post exercise of a single exercise session)
  • Changes for resting glucose from pre- to 15 min post-exercise(Immediately pr to 15 min post-exercise of a single exercise session)

研究者

发起方
University of Erlangen-Nürnberg Medical School
申办方类型
Other
责任方
Sponsor

研究点 (2)

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