A Study on the Effectiveness of IFA Supplementation, Deworming, and Nutrition Education in Addressing Anemia Among Adolescent Girls in Two Counties in Liberia
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Change in participants' hemoglobin level from enrollment to completion of the study
研究概览
简要总结
The purpose of this study is to evaluate the feasibility and effectiveness of weekly iron and folic acid (IFA) supplementation and one-time deworming treatment at the community level in improving hemoglobin levels among adolescent girls in Liberia, West Africa, and to assess the feasibility and effectiveness of a targeted nutrition education program in improving nutrition knowledge, attitudes, and practices in the same population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 10 Years 至 19 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Adolescent girl aged 10 - 19 years at the time of enrollment
- •Lives within the selected study communities in Montserrado or Margibi counties
- •Caregiver/adolescent consents to participate in the study
排除标准
- •Currently pregnant
- •Active malaria infection as defined by positive rapid diagnostic test (RDT)
- •Severe acute malnutrition at the time of enrollment
- •Known malignancy
- •Known sickle cell disease
研究组 & 干预措施
Nutrition+ Intervention
This group will receive a structured nutrition education package provided by Community Health Assistants (CHAs) based on a handbook on nutrition education developed by UNICEF with collaboration from the Liberia Ministry of Health. The structured nutrition education package will focus on four key areas: causes and prevention of anemia, healthy eating and food choices, hand washing, and physical exercise. Participants in the intervention group will also receive IFA supplementation on a weekly basis for the duration of the study, and a one-time oral deworming treatment (mebendazole), which will be administered once at the beginning of the study.
干预措施: Iron and folic acid (IFA) supplementation (Dietary Supplement)
Nutrition+ Intervention
This group will receive a structured nutrition education package provided by Community Health Assistants (CHAs) based on a handbook on nutrition education developed by UNICEF with collaboration from the Liberia Ministry of Health. The structured nutrition education package will focus on four key areas: causes and prevention of anemia, healthy eating and food choices, hand washing, and physical exercise. Participants in the intervention group will also receive IFA supplementation on a weekly basis for the duration of the study, and a one-time oral deworming treatment (mebendazole), which will be administered once at the beginning of the study.
干预措施: Targeted nutrition education (Behavioral)
Nutrition+ Intervention
This group will receive a structured nutrition education package provided by Community Health Assistants (CHAs) based on a handbook on nutrition education developed by UNICEF with collaboration from the Liberia Ministry of Health. The structured nutrition education package will focus on four key areas: causes and prevention of anemia, healthy eating and food choices, hand washing, and physical exercise. Participants in the intervention group will also receive IFA supplementation on a weekly basis for the duration of the study, and a one-time oral deworming treatment (mebendazole), which will be administered once at the beginning of the study.
干预措施: Mebendazole Pill (Drug)
Control group - standard services only
This group will receive only the current package of basic nutrition services provided at the health facility and at community level by health workers and CHAs, respectively.
干预措施: Standard nutrition services (Other)
结局指标
主要结局
Change in participants' hemoglobin level from enrollment to completion of the study
时间窗: Baseline and Week 12
Point of care hemoglobin testing will be conducted at enrollment and at the conclusion of the study.
次要结局
- Changes in responses to questions in the Nutrition Knowledge, Attitudes, and Practice (KAP) survey from baseline to follow up evaluation(Baseline and Week 12)
- Feasibility of targeted intervention for scale-up to country-wide enhanced nutrition services(12 weeks)
研究者
Julia Rubin-Smith
Global Health Faculty/Assistant in Medicine
Boston Children's Hospital