A clinical study to assess the flow rate of major salivary glands among various types of smokers using modified Schirmers method

Active, not recruiting

• Conditions: Disturbances of salivary secretion,

• Registration Number: CTRI/2022/06/043554
• Lead Sponsor: M Jyothi Pravallika

Brief Summary

This study is an observational study to assess the flow rate of major salivary glands in various types of smokers using modified schirmer’s method. Total sample size comprised of 66 subjects divided into 3 groups. Each group comprising of 22 subjects, each divided into conventional smokers, reverse smokers and nonsmokers. Measurement of unstimulated whole mouth salivary flow for three minutes was performed using “Modified Schirmer Methodâ€. The sample collection will be done between 9 a.m. and 12 p.m. All the participants are asked to refrained from eating, drinking and smoking 1 hour prior to the study. The subjects are asked to sit in an upright position and to raise and slowly retract their tongue, to avoid unintentional wetting of the Schirmer test’s strip. The strip will be kept in front of the parotid gland duct i.e., at the papilla in oral cavity just opposite to the maxillary 2nd molar crown for parotid gland and for submandibular gland the strip will be kept vertically with the help of cotton pliers, while the bottom of the paper was kept in contact with the floor of the mouth. The length of the wet area on the strip was recorded at the intervals of 1, 2 and 3 minutes. The results were subjected to statistical analysis.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-30
• Last Update Posted: 2024-05-27

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• subjects who are having habit of conventional smoking 2.
• subjects who are having habit of reverse smoking 3.
• subjects who are healthy and have no habit of smoking.

Exclusion Criteria

• subjects with systemic or nervous disease that could interfere with glandular functioning.
• (Parkinson’s disease) 2.
• Subjects who take any medicines that could interfere with saliva secretion.(sympathomimetics like ephedrine, phenylephrine etc.,) 3.
• Subjects with symptoms of oral dryness with no habit of smoking.
• (sjogren’s syndrome) 4.
• Any subject who had undergone radiotherapy of head and neck procedures recently.
• Subjects who are having habit of smoking previously and has quit more than 3 months back.
• Subjects who are not willing to participate in study after explanation of the procedure are excluded.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
•To know the change in the flow rates of major salivary glands in various types of smoking habits.	PAROTID GLAND FLOW RATE: 1ST DAY | SUBMANDIBULAR GLAND FLOW RATE: 1ST DAY

Trial Locations

Locations (1)

Vishnu Dental College; 🇮🇳 Godavari, ANDHRA PRADESH, India

Vishnu Dental College

🇮🇳Godavari, ANDHRA PRADESH, India

M Jyothi Pravallika

Principal investigator

9948968999

jyothipravallika.meka@vdc.edu.in