The effect of Utrica dioica extract on Glucose level and AMPK (Adenosine Monophosphate Activated Protein Kinase)enzyme
Phase 2
- Conditions
- type 2 diabet.Non-insulin-dependent diabetes mellitus type 2
- Registration Number
- IRCT2014100119364N1
- Lead Sponsor
- Vice chancellor for research,Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Fasting blood sugar between110- 200 mg/dl; Taking usual diabetes medicines that donot have effect on AMPK enzyme level like metformin and thiazolidinediones;
Exclusion criteria:Illness background kidney; cardiovascular; liver.
Taking usual diabetes medicines that have effect on AMPK enzyame level like metformin and thiazolidinediones; Pregnancy and Lactating; insulin injection; Smoking and use of alcohol; change in diet and exercise.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AMPK (Adenosine Monophosphate Activated Protein Kinaseenzme level. Timepoint: Befor & after intervention. Method of measurement: Immune assay.;Glucose blood level. Timepoint: befor & after intervention. Method of measurement: spectrophotometric assay(kit).
- Secondary Outcome Measures
Name Time Method Hb A1C. Timepoint: Before & after intervention. Method of measurement: Spectrophotometric assay (kit).;Insulin. Timepoint: Before & after intervention. Method of measurement: Immune assay.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does Hydroalcholic aerial parts of Utrica dioica extract activate AMPK and improve glucose metabolism in type 2 diabetes?
What is the comparative efficacy of Utrica dioica extract versus metformin in regulating glucose and AMPK activation in type 2 diabetes?
Which biomarkers predict response to Utrica dioica extract's AMPK modulation in type 2 diabetic patients?
What are the adverse events associated with Utrica dioica extract in phase II trials for type 2 diabetes compared to standard therapies?
How does Utrica dioica extract synergize with thiazolidinediones in AMPK-dependent glucose regulation for type 2 diabetes?