Talking With Voices

Not Applicable

Completed

• Conditions: Schizophrenia spectrum disorder; Mental and Behavioural Disorders; Schizophrenia, schizotypal and delusional disorders

• Registration Number: ISRCTN45308981
• Lead Sponsor: Greater Manchester Mental Health NHS Foundation Trust

Brief Summary

2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33629816/ (added 29/10/2021) 2021 Other publications in https://pubmed.ncbi.nlm.nih.gov/34762756/ clinical perspectives and experiences publication (added 24/03/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36423442/ primary outcomes (added 25/11/2022) 2023 Other publications in https://pubmed.ncbi.nlm.nih.gov/37551953 Qualitative results on service user perspectives (added 14/08/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-15
• Study Completion: 2020-12-30
• Last Update Posted: 23 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Current inclusion criteria as of 15/05/2019:
1. Adults aged =18 years
2. Who have heard voices for at least one year and score =4 on the auditory hallucination subscale of the Positive and Negative Syndrome Scale (PANSS)
3. Who have had no changes to medication within the past month
4. Who meet criteria for ICD schizophrenia spectrum disorder
5. Who are able to provide written, informed consent
6. Who are not currently receiving structured psychological therapy for psychosis
7. Who are in contact with secondary care mental health services and have a care coordinator
8. Who are willing and able to communicate with their voices and relay what the voices say to a therapist
9. Whose voices are sufficiently personified to engage in dialogical work (i.e., voices which can engage in conversation and dynamically interact with the hearer)

Previous inclusion criteria from 07/06/2018 to 15/05/2019:
1. Aged =18 years
2. Has heard voices for at least 1 year and score =4 on the auditory hallucination subscale of the Positive and Negative Syndrome Scale (PANSS)
3. Has had no changes to medication within the past month
4. Meets criteria for ICD schizophrenia spectrum disorder
5. Able to provide written, informed consent
6. Not currently receiving structured psychological therapy for psychosis
7. In contact with secondary care mental health services and has a care coordinator
8. Willing and able to communicate with the voices and relay what the voices say to a therapist
9. Voices are sufficiently personified to engage in dialogical work (i.e. voices that can engage in conversation and dynamically interact with the hearer)

Original inclusion criteria:
1. Aged =18
2. Have heard voices for at least one year and score =4 on the auditory hallucination subscale of the Positive and Negative Syndrome Scale for Schizophrenia (PANSS)
3. Have had no changes to medication within the past month
4. Have a lifetime diagnosis of ICD schizophrenia spectrum disorder
5. Able to provide written, informed consent
6. Not currently receiving, or waiting to receive, cognitive behavioural therapy for psychosis
7. Willing and able to communicate with their voices and relay what the voices say to a therapist
8. Whose voices are sufficiently personified to engage in dialogical work (i.e. voices which can engage in conversation and dynamically interact with the hearer)
9. No restrictions have been placed on recruitment according to gender

Exclusion Criteria

1. At immediate risk of harm to self or others
2. Non-English speaking
3. Primary diagnosis of alcohol/substance dependence or autism spectrum disorder
4. Moderate/severe learning disability
5. Organic brain injury or illness implicated in the aetiology of psychotic symptoms
6. A score of > 5 on the conceptual disorganisation subscale of the Positive and Negative Syndrome Scale for Schizophrenia
7. Homeless and/or of no fixed abode

Study & Design

• Study Type: Interventional
• Study Design: Not specified