Pilot Survey of Dengue Fever in Solomon Islands

Completed

• Conditions: Arbovirus Infections

• Registration Number: NCT01868399
• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital

Brief Summary

Since 2009, Kaohsiung Medical University Hospital organized a medical team to provide the medical service for people in Solomon Islands thru Taiwan Health Center at the local. In addition to Malaria and pulmonary tuberculosis, the investigators also found dengue virus, Japanese Encephalitis virus, Chikungunya virus infections and intestinal parasitic infections might be the existing but overlooked and neglected medical issues in Solomon Islands. These infections show similarity in clinical manifestations and usually difficulty in clinical diagnosis, instead these infections rely on the laboratory identification with good laboratory quality and facility.

Detailed Description

In this study, the investigators plan to investigate the local people, either from the community or the hospitals, to identify the prevalence and incidence of dengue fever, including laboratory identification of related infections for differential diagnosis, including Japanese Encephalitis virus, Chikungunya virus and intestinal parasitic infections. Intestinal parasite survey has been the routine long-term service offered by the Kaohsiung Medical University Hospital in Solomon Islands. At the same time, the subjects enrolled in this study will also be asked the common medical illness in Solomon Islands (i.e. malaria, pulmonary tuberculosis and metabolic syndrome etc.) in order to delineate the association of dengue fever and these acute and chronic illness.

Study Timeline

• Study Start: 2013-03-22
• Study First Submitted: 2013-05-27
• Study First Submitted QC: 2013-05-30
• Study First Posted: 2013-06-04
• Status Verified: 2016-08
• Primary Completion: 2016-12-31
• Study Completion: 2016-12-31
• Last Update Submitted: 2017-03-05
• Last Update Posted: 2017-03-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2200

Inclusion Criteria

• healthy volunteer
• reported dengue virus infection volunteer
• people who understand the purpose of the study and agree the to sign the informed consent

Exclusion Criteria

• people who refuse to join the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dengue fever	at the time of sampling (blood)	Clinical manifestations, comorbidity and severity

Secondary Outcome Measures

Name	Time	Method
Co-infection and interplay of dengue-like pathogens	within the first 3 months after blood sampling	Identification and Analysis of dengue-like illness and pathogens to investigate the interplay between these coinfections

Trial Locations

Locations (1)

Tropical Medicine center; 🇨🇳 Kaohsiung city, Taiwan