Polyphenol Rich Supplementation on Markers of Recovery From Intense Resistance Exercise
Trial Snapshot
- Phase
- Phase 1
- Sponsor
- Jacksonville University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Assessment of Oxidative Stress
Study Overview
Brief Summary
Strength training is commonly used as an intervention to increase muscle mass, thus improving a person's ability to undertake activities of daily living, or enhance athletic performance. The strength training regimen itself, while ultimately having beneficial effects, causes muscle fibers to be damaged, which the body has to recover from. As the body recovers, it rebuilds the muscle tissue and after multiple consecutive bouts of strength training, the muscle eventually becomes larger and stronger. Thus, it is the recovery from strength training exercise that ultimately determines how well the body adapts. Where inadequate recovery could eventually lead to overtraining and/or injury, optimizing the recovery process from strength training could maximize strength training adaptations. This concept of optimizing recovery has led to development of many supplements, including antioxidants, which may reduce the damage associated with strength training activities and therefore enhance positive adaptations. The purpose of this study is to assess the ability of a polyphenol rich supplementation to aid the recovery process from a demanding bout of resistance exercise
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Basic Science
- Masking
- Double (Participant, Investigator)
Masking Description
To ensure that all subjects and researchers are unaware of the treatment assignments we will have one outside individual that will possess the knowledge of which subjects are given which supplement and which were given a placebo. This information will remain confidential until the study has been concluded. At the conclusion of the study, participants will be informed of which condition they were assigned. in an event of an emergency or the participant decides not to participate his condition will be revealed.
Eligibility Criteria
- Ages
- 21 Years to 45 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •6 months of resistance training experience with barbel back squat exercise
Exclusion Criteria
- •Not currently taking any antioxidant supplements, not currently using any hormone replacement therapy or anabolic androgenic steroids.
Arms & Interventions
Placebo
Rice flour capsule
Intervention: Placebo Oral Capsule [CEBOCAP] (Other)
Polyphenol Rich Supplement
NordicCherry Tart Cherry Extract Powder 500 mg in capsule form
Intervention: Tart Cherry (Dietary Supplement)
Outcomes
Primary Outcomes
Assessment of Oxidative Stress
Time Frame: 7 weeks
Blood analyses will be used, 8 mL of blood will be taken from the participant six times per condition. The blood will be centrifuged to separate the serum/ plasma and analyzed by enzyme- linked immunosorbent assay (ELISA) for c- reactive protein and creatine kinase, and oxidative damage
Secondary Outcomes
- Muscle soreness(7 weeks)
- Vertical Jump Performance(7 weeks)