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IOP Changes Associated With SICS and Phako

Early Phase 1
Completed
Conditions
Cataract
Glaucoma
Interventions
Procedure: cataract surgery
Registration Number
NCT02642211
Lead Sponsor
Robin, Alan L., M.D.
Brief Summary

Prospective randomized trial in patients requiring cataract surgery in which IOP, angle anatomy and other demographic and clinical data are compared. Subjects randomized to both MSICS and phakoemulsification

Detailed Description

Prospective, randomized, double masked, parallel assignment clincal trial. Five hundred eyes of 500 participants between 40 - 70 years with normal IOP, gonioscopically open angles and age related cataract. Eyes underwent phacoemulsification or MSICS following a 1:1 randomization and allocation code. Best corrected vision (BCVA), IOP, comprehensive slit lamp evaluation and anterior segment optical coherence tomography (ASOCT) were performed at baseline and at 1, 3 and 6 months follow up.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
500
Inclusion Criteria

Age over 40 requiring cataract surgery -

Exclusion Criteria

inability to follow up, lens not suitable for phacoemulsification, prior intraocular surgery, glaucoma

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
MSICScataract surgeryEyes undergoing manual small incision cataract surgery
phakocataract surgeryeyes receiving phakoemulsification for cataract surgery
Primary Outcome Measures
NameTimeMethod
Intraocular pressure lowering6 months

intraocular pressure measured with aplanation tonometry

Secondary Outcome Measures
NameTimeMethod
Angle anatomy6 months

OCT changes in angle anatomy

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