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Clinical Trials/NCT00856102
NCT00856102
Completed
Not Applicable

Efficacy of Exercise in Promotion Cognitive-psychosocial Functions in Men With Prostate Cancer Receiving Androgen Depletion Therapy

University of Manitoba1 site in 1 country30 target enrollmentMarch 2009
ConditionsProstate Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prostate Cancer
Sponsor
University of Manitoba
Enrollment
30
Locations
1
Primary Endpoint
Cognitive-psychosocial functions
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

The objective of the proposed research is to determine the efficacy of a home-based walking exercise program in promoting cognitive-psychosocial functions of men with prostate cancer receiving androgen depletion therapy (ADT). ADT is the mainstay treatment for men with advanced prostate cancer. However, ADT has a number of side effects including compromised cognitive function, depression and anxiety, which negatively impacts the quality of life of men with prostate cancer. The central question of the proposed research is to determine if exercise will have a positive impact on the quality of life of men with prostate cancer undergoing ADT.

Hypothesis:

Registry
clinicaltrials.gov
Start Date
March 2009
End Date
December 2010
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Eligibility Criteria

Inclusion Criteria

  • men aged 50 or older
  • diagnosed with adenocarcinoma prostate cancer
  • will initiate and receive continuous ADT (LHRH or combination of LHRH and anti-androgen for at least 6 months

Exclusion Criteria

  • severe cardiac disease (New York Heart Association class III or greater)
  • severe osteoporosis
  • uncontrolled hypertension
  • orthostastic blood pressure drop \> 20mm Hg
  • moderate to severe aortic stenosis
  • acute illness or fever
  • uncontrolled atrial or ventricular dysrhythmias
  • uncontrolled sinus tachycardia (\> 120 beats per minute)
  • uncontrolled congestive heart failure
  • third-degree atrio-ventricular heart block

Outcomes

Primary Outcomes

Cognitive-psychosocial functions

Time Frame: 3 and 6 months

Secondary Outcomes

  • health-related quality of life(3 and 6 months)

Study Sites (1)

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