NCT00856102已完成不适用
Efficacy of Exercise in Promotion Cognitive-psychosocial Functions in Men With Prostate Cancer Receiving Androgen Depletion Therapy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Cognitive-psychosocial functions
研究概览
简要总结
The objective of the proposed research is to determine the efficacy of a home-based walking exercise program in promoting cognitive-psychosocial functions of men with prostate cancer receiving androgen depletion therapy (ADT). ADT is the mainstay treatment for men with advanced prostate cancer. However, ADT has a number of side effects including compromised cognitive function, depression and anxiety, which negatively impacts the quality of life of men with prostate cancer. The central question of the proposed research is to determine if exercise will have a positive impact on the quality of life of men with prostate cancer undergoing ADT.
Hypothesis:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •men aged 50 or older
- •diagnosed with adenocarcinoma prostate cancer
- •will initiate and receive continuous ADT (LHRH or combination of LHRH and anti-androgen for at least 6 months
排除标准
- •severe cardiac disease (New York Heart Association class III or greater)
- •severe osteoporosis
- •uncontrolled hypertension
- •orthostastic blood pressure drop > 20mm Hg
- •moderate to severe aortic stenosis
- •acute illness or fever
- •uncontrolled atrial or ventricular dysrhythmias
- •uncontrolled sinus tachycardia (> 120 beats per minute)
- •uncontrolled congestive heart failure
- •third-degree atrio-ventricular heart block
- •active pericarditis or myocarditis
- •recent embolism, thrombophlebitis
- •deep vein thrombosis, resting ST displacement
- •uncontrolled diabetes
- •uncontrolled pain
- •cognitive impairment
- •history of falls due to balance impairment or lost of consciousness
- •severe neuromusculoskeletal conditions that limit their ability to perform walking exercise
结局指标
主要结局
Cognitive-psychosocial functions
时间窗: 3 and 6 months
次要结局
- health-related quality of life(3 and 6 months)
研究者
研究点 (2)
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