Comparative Evaluation of the Sutureless and Multiple Suture Technique in Third Molar Impaction: A Clinical Trial
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Pain
研究概览
简要总结
Comparative evaluation of the sutureless and multiple suture technique in third molar impaction: a clinical TRIAL
One of the most frequent procedures in oral and maxillofacial surgery is the surgical extraction of mandibular third molars. The average incidence of third molar impaction is 24.40% approximately with significant regional variations1. Although environmental characteristics are more likely to be the cause of these differences, genetic factors may play a role. Primary closure of the operating site is usually advocated but is not always essential as advocated by the French Health Authority (HAS)2. There is still debate regarding the optimal surgical methods, particularly with regards to the mucosal closure after surgical removal of impacted mandibular third molar. The two approaches used are to allow for healing by either primary or secondary intention. Suturing of sockets after extraction is recommended by some groups on the grounds that wound approximation help in bleeding control and decreases the contamination of operative site and therefore, enhance the rate and quality of healing. Others, however, favor healing by secondary intention because it allows the surgical site to naturally drain, lowering the risk of inflammatory response. Dubois et al. compared hermetic closure to sites where the mesial portion of the wound was allowed to heal through secondary intention.3
On the fifth day, wound dehiscence was noted in fifty percent of the hermetically sutured patients, though no infection was present. They also found that sutured patients had a tendency for incomplete closure, even though there were no changes in postoperative swelling, pain, or infection. Following the extraction of an impacted wisdom tooth, subsequent research has compared surgical site closure methods.4–6. None, however, have assessed quality of life, pain, oedema, trismus, complications, and the use of painkillers after more than seven days following surgery in a sizable cohort. Although the results showed significant heterogeneity because of the variations in the incision techniques used, a meta-analysis of five studies found that secondary closure reduced pain7. There is currently not enough data to determine whether alveolar osteitis, infection, or bleeding responds better to primary or secondary healing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •American Society of Anaesthesiologists (ASA) physical status I subjects between 20 and 50 years of age, both male and female were included in the study.
- •Indications for extraction of a single impacted mandibular third molar under local anaesthesia -Patients with mesioangular, distoangular, horizontal and vertical impactions according to Winter’s classification -Absence of symptoms such as facial swelling or limited mouth opening from any cause within 5 days preceding surgery.
排除标准
- •Pregnant females, lactating mothers.
- •History of allergy to the drugs used in this study.
- •Patients not willing for the procedure or not willing to give written informed consent.
- •Medically compromised patients.
结局指标
主要结局
Pain
时间窗: Post-operative day 7
次要结局
- Pain, Oedema, trismus, complications, flap healing in the experimental arm, analgesic consumption, Quality of life(DAY 0, 7 AND 28)
研究者
ISHITA RANGNANI
KOTHIWAL DENTAL COLLEGE AND RESEARCH CENTRE
