A double blind, placebo controlled, randomized, cross-over study to assess the effects of polydextrose on appetite suppression and its mechanisms of action in healthy women with a normal weight and overweight female participants - JZ PDX Satiety

TNO0 个研究点目标入组 32 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•1.Healthy female participants aged 20-45 years inclusive;
•2.BMI: 20-30 kg/m2 inclusive;
•3.Written consent regarding participation after full information regarding all details of the study;
•4.Normal Dutch eating habits (consuming mostly three main meals per day; used to eat bread for lunch);

•1.Pregnancy;
•2.On-going or recent treatment for diabetes, hypertension, coronary heart disease, psychiatric conditions, inflammatory chronic disease - rheumatoid arthritis, Crohn Disease, ulcerous colitis, chronic constipation, eating disorders, or any disease condition which interferes with ADME of the investigational product;
•3.Reported postmenopausal;
•4.Having menstruation problems, e.g. PCOS;
•5.Reported to be on a slimming diet or other dietary treatment (currently or during last two months, like vegetarian diet, lactose restricted diet etc.);
•6.Aversion towards products (yoghurt) provided in the study;
•7.On-going use of any slimming preparations;
•8.Any kind of dysfunction of digestive tract, food allergy, chronic constipation, recent/actual gastroenteritis;
•9.Restrained eaters
•10.Participants consuming more than 23 g of dietary fiber per day
•11.Smoker in the last 3 months;
•12.Heavy coffee drinkers (more than 6 cups a day);
•13.High level of physical activity
•14.Heavy alcohol consumers

发起方

TNO