Anxiety, Depression and Substance Use in Latin American Countries With Different Economic Incomes During the Covid-19 Pandemic.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 3,022
- 试验地点
- 1
- 主要终点
- Alcohol, Smoking and Substance Involvement Screening Test (ASSIST)
研究概览
简要总结
The Covid-19 pandemic has generated, in the Latin American population, unprecedented levels of anxiety, depression and substance use associated with the diagnosis of the disease. Consequently, it has been pointed out that a moderating variable for the appearance of these psychological problems is high social and economic vulnerability. OBJECTIVE: To assess differences in psychological problems exposed to the diagnosis of Covid-19 by groups of countries with different incomes. METHODOLOGY: A non-experimental, correlational, prospective, double-blind, cross-sectional study was carried out using the CHERRIES methodological criteria and the sample was Latin American people. The scales used were for depression (PHQ-9), anxiety (GAD-7) and substance use (ASSIST). Likewise, Latin American countries were classified by their income level according to the World Bank. Also, the Shapiro-Wilk normality test and an ANOVA analysis of variance were performed, with Post Hoc test, with Bonferroni adjustment
详细描述
Sampling:
A non-experimental sampling by volunteer subjects is performed, since the subjects will come to the study by a call on social networks.
Data management plan:
Data dictionary design
Training will be provided and data dictionary will be developed describing the properties of variables such as data type (e.g. string and number), variable size, data encoding, and constraints and validations attached to a given variable (Annex).
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Living in Latin America during the Covid-19 pandemic
- •Be between 18 and 65 years of age
- •Be able to read and write
- •Be a native Spanish speaker
- •Agree to voluntarily participate in the study
排除标准
- •Persons receiving psychological or psychiatric treatment during the study period.
- •Persons who have suffered the loss of a family member in at least 1 month prior to the Covid-19 evaluation.
- •Persons who have migrated to another Latin American country in at least 6 months.
- •Persons who have been hospitalized in the last month.
- •Persons who reside in Latin America, but are not natives.
- •Have a confirmed diagnosis of Covid-19 within the last 2 weeks.
- •Persons who are minors or over 65 years of age
结局指标
主要结局
Alcohol, Smoking and Substance Involvement Screening Test (ASSIST)
时间窗: 3 months
Validation and cultural adaptation was carried out in university students through a non-experimental ex post facto study with 1,176 undergraduate students, mostly women (70.1%) aged 18 to 23 years (89.5%) and unmarried (87.5%). Concurrent validity was obtained by factor analysis and reliability and correlation tests between the alcohol subscale and AUDIT, the Tobacco subscale and Fargerström's Tes, and the marijuana subscale and the DAST-20. The results found adequate reliability coefficients for the ASSIST subscales for tobacco (alpha = 0.83), alcohol (alpha = 0.76) and marijuana (alpha = 0.73). Regarding interscale correlation, significant correlations were only found with the AUDIT (r = 0.71) and the alcohol subscale.
Patient Health Questionnaire-9 (PHQ-9)
时间窗: 2 weeks
It is a cross-culturally validated instrument and its confirmatory factor analysis suggested that the one-factor structure was a reasonably good fit. The internal consistency of the PHQ-9 was good (Cronbach's alpha\> = 0.8) overall and for subgroups defined by gender, literacy, and age. The PHQ-9 demonstrated good predictive validity: participants with a PHQ-9 diagnosis of depression had lower quality of life scores on the overall WHOQOL-BREF scale and on each of its domains. Using the results of the PHQ-9 as a gold standard, the optimal cut-off score of 10. Definition of the variable: A depressive episode is characterized by a period of depressed mood or decreased interest in activities occurring most of the day, almost every day for a period lasting at least two weeks accompanied by other symptoms such as difficulty concentrating, feelings of worthlessness or excessive or inappropriate guilt.
Generalized Anxiety Disorder scale (GAD-7):
时间窗: 2 weeks
The GAD-7 consists of the 7 items with the highest correlation with the total score of the 13-item scale (r = 0.75-0.85). It is an instrument with cross-cultural validation and analysis of receiver operating characteristics with this set of items showed an area under the curve (0.906) and scales with as much as the full 13-item set. These 7 items also had the highest rank correlations in the development sample (n = 1184) and the 2 replication samples (n = 965 and n = 591). The 2 core criteria (A and B) of the DSM-IV definition of GAD are captured by the first 3 items of the scale.26 Of note, 6 of the 7 items had the highest divergent validity (ie, the largest difference between item-total scale score correlation and item-PHQ-8 depression score correlation \[Δ r = 0.16-0.21\]). Because each of the 7 items is scored from 0 to 3, the GAD-7 scale score ranges from 0 to 21.
次要结局
未报告次要终点
研究者
Alejandro Hernández Posadas
Full-time teacher and researcher.
Universidad Westhill, Facultad de Psicología