Comparison of dose response to two different doses of intravenous lidocaine for postoperative analgesia in patients undergoing elective laparoscopic gynaecological oncology surgery under general anaesthesia : A Prospective randomised controlled study

This is a randomised controlled study comparing the dose response of two different doses of intravenous lidocaine for post operative analgesia. In patients undergoing laparoscopic gynaecological oncologic surgery , patients are allocated into two groups. Patients in group A will receive an intravenous lidocaine bolus of 1.5 mg/kg slowly over 10 mins prior to induction followed by a continuous infusion at the rate of 1.5mg/kg/hour via infusion pump. Patients in group B will receive an intravenous lidocaine bolus of 1.5 mg/kg slowly over 10 mins prior to induction followed by a continuous infusion at the rate of 2 mg/kg/hour via infusion pump. Maintenance of anaesthesia is same in both groups. Primary objective of this study is to assess visual analogue pain score in post operative period and secondary objectives are intraoperative hemodynamic stability, intraoperative opioid requirement , assessing time to first analgesic dose, total consumption of rescue analgesic in 24 hours and side effects of intravenous lidocaine.