Therapeutic Effects of Topical Herbal Medicine on Rosacea
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Reduction of Flushing, Erythema, Telangiectasia, Papules, and Pustules
研究概览
简要总结
The aim of this study is to investigate the effects of topical herbal medicine in the patients with rosacea.
详细描述
Rosacea is a chronic inflammatory disorder which affects the cheek, nose, chin, forehead and eyes. It is typically characterized by cutaneous signs such as flushing, erythema, telangiectasia, papules, and pustules in the face. The pathogenic mechanism of rosacea is unknown, and there is no cure for rosacea. The therapeutic approaches include oral medicine, topical medicine and surgical interventions depending on the different subtypes of rosacea. The recent study demonstrates that combination therapy may be more effectively improved the symptoms of rosacea. Dian dao san is a topical herbal compound for reducing the features as flushing, erythema, papules, and pustules for years. The investigators hypothesize that dian dao san can be more beneficial in treating the patients with rosacea and improving the quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Willing to sign inform consent
- •Aged above 20 years old with rosacea
- •No treatment for rosacea within 2 weeks
排除标准
- •With malignant lesion in the rosacea lesion
- •Rosacea lesion with high risk of infection
- •Allergy to Chinese herbal medicine patch or ointment
- •Pregnancy
研究组 & 干预措施
group A (dian dao san group)
Herbal medicine (dian dao san) will be applied to the lesions of rosacea twice a day. Subject will receive persistent treatment for 6 weeks.
干预措施: dian dao san (Drug)
group B( topical medicine without therapeutic effects)
Placebo (topical medicine without therapeutic effects) will be applied to the lesions of rosacea twice a day. Subject will receive persistent treatment for 6 weeks.
干预措施: dian dao san (Drug)
结局指标
主要结局
Reduction of Flushing, Erythema, Telangiectasia, Papules, and Pustules
时间窗: 6 weeks
quantified by Investigator Global Assessment, IGA. IGA is used in the study for assessing the severity of rosacea ranging from 0 (clean) to 4 (most severe).
次要结局
- Dermatology Quality of Life Index, DQoL(6 weeks)
