Factors of Control Hypertension or Type 2 Diabetes on the Severity of Stroke and Survival Rates Within 1 Year in Trat

Completed

• Conditions: Stroke; Type2diabetes; Hypertension
• Interventions: Other: Severity of Stroke and 1 year survival

• Registration Number: NCT06288269
• Lead Sponsor: Phrapokklao Hospital,Thailand

Brief Summary

The purpose of this study was to study factors for controlling hypertension or type 2 diabetes before stroke diagnosis on the severity level when a stroke occurs, NIHSS, and survival rate after having a stroke in 1 year in Trat Province The research hypothesis was patients with hypertension or type 2 diabetes who are well-controlled Will have a lower NIHSS score than the group whose disease is not well-controlled. and patients with hypertension or type 2 diabetes that is well controlled There will be a higher survival rate for patients diagnosed with cerebrovascular disease within 1 year than those whose disease cannot be controlled.

Detailed Description

BACKGROUND: Situation of Non-communicable disease groups. It was the number one health problem in the world. The situation in Thailand from 2017-2022 found an increase in the number of new diagnoses and death cases from stroke patients. For the situation in Trat Province, it was found that the situation of sickness rates tend to be stable. As for the death rate per 100,000 people from stroke, there was a continuous upward trend. Therefore, a research project was organized to study the factors of control disease (hypertension or non-insulin-dependent diabetes mellitus type 2) on the severity of stroke and survival rates within 1 year to be used as information for further patient care.

OBJECTIVES: To study factors that influence the severity of stroke and correlate with survival rates within 1 year in Trat Province.

METHODS: This is a retrospective analytic cohort study. Data was collected using a Case Record Form (CRF) to record information on a total of 291 cases of hypertension and non-insulin-dependent diabetes mellitus type 2 patients who entered the stroke treatment system at Trat Hospital in the year 2022. Data were analyzed by Chi-square statistics to test the relationship of NCD control with the severity of stroke and using Kaplan-Meier Curve test hypotheses for comparing survival rates using Log-rank test statistics.

Study Timeline

• Study Start: 2023-11-01
• Primary Completion: 2023-12-30
• Study Completion: 2024-01-15
• Study First Submitted: 2024-02-02
• Study First Submitted QC: 2024-02-24
• Status Verified: 2024-03
• Study First Posted: 2024-03-01
• Last Update Submitted: 2024-03-05
• Last Update Posted: 2024-03-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 291

Inclusion Criteria

• Patients who have chronic hypertension or type 2 diabetes with a history of illness of at least 1 year before the stroke.
• Patients had a new stroke for the first time in his life, including an ischemic stroke. hemorrhagic stroke and hemorrhage in the brain
• The patient was confirmed by CT scan
• Thai nationality.

Exclusion Criteria

• Patients diagnosed with cerebrovascular disease who have a previous history of ischemic or hemorrhagic stroke.
• Patients diagnosed with transient ischemic attack
• Patients who have a history of chronic disease that are at high risk of having a stroke, such as being a pregnant patient, still taking birth control pills.
• There are certain genetic diseases, such as antiphospholipid syndrome
• Patients had previous history of brain aneurysm, extracranial arterial dissection, atrial fibrillation, drug addict use, etc.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control of Hypertension or/and Type 2 Diabetic	Severity of Stroke and 1 year survival	Control disease of HT Control disease of DM2 Control disease of HT plus DM2
Uncontrol of Hypertension or/and Type 2 Diabetic	Severity of Stroke and 1 year survival	Uncontrol disease of HT Uncontrol disease of DM2 Uncontrol disease of HT plus DM2

Primary Outcome Measures

Name	Time	Method
1 year survival death	1 year after stroke attack	Patients with new stroke case with different diseases control will have different death rate in 1 year
Stroke severity was assessed using the National Institute of Health Stroke Scale (Clinical Mild NIHSS = 0-4 and Clinical Moderate to severe NIHSS = 5-42)	Results of controlling diabetes and hypertension in the 1-3 year period before having a stroke.	Patients with new stroke case with different diseases control will have different severity of stroke.

Trial Locations

Locations (1)

Trat Provincial Public Health Office; 🇹🇭 Trat, Thailand