Prevalence of Non-alcoholic Fatty Liver Disease in Patients With Chronic Kidney Disease in Assiut

Not yet recruiting

• Conditions: CKD; NAFLD

• Registration Number: NCT06009250
• Lead Sponsor: Muhammad Ameen Abdelrady Abdelaziz

Brief Summary

The goal of this observational study is to detect the prevalence of NAFLD in CKD patients

The main question\[s\] it aims to answer are:

* \[question 1\] prevalence of NAFLD in CKD patients.

* \[question 2\] the relationship between NAFLD and CKD.

Detailed Description

The goal of this observational study is to detect the prevalence of NAFLD in CKD patients

The main question\[s\] it aims to answer are:

* \[question 1\] prevalence of NAFLD in CKD patients.

* \[question 2\] the relationship between NAFLD and CKD.

Study Timeline

• Study First Submitted: 2023-07-28
• Status Verified: 2023-08
• Study First Submitted QC: 2023-08-22
• Last Update Submitted: 2023-08-22
• Study First Posted: 2023-08-24
• Last Update Posted: 2023-08-24
• Study Start: 2023-12
• Primary Completion: 2024-12
• Study Completion: 2024-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• CKD patients

Exclusion Criteria

• HCV and HBV Positive patients
• Alcoholics
• patient on Hemodialysis
• patients with wilson disease
• patients with alpha one antitrypsin deficiency

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
abdominal ultrasound	1 year	assessment of Liver regarding fatty liver disease by Ultrasound.
Complete Blood Picture (WBCs, HB, Patelets	1 year	total leucocytic count Hemoglobin level and platelet count will be assessed in our patients and will be reported in a table
Fibroscan	1 year	participants will undergo fibroscanning of the liver to assess NAFLD and results will be reported in a table.
Lipid Profile	1 year	participants will be assessed regarding Cholesterol level, Triglycerides, HDL and LDL. results will be reported in a table
liver enzymes	1 year	participants will undergo assessment of liver enzymes (AST and ALT) and results will be reporeted in a table.
BUN, Cr level and estimated GFR	1 year	participants will be assessed regarding BUN, CR and estimated GFR to confirm and follow up CKD patients involved in the study.
serum Uric Acid	1 year	serum uric acid will be assessed and reported in our patients

Secondary Outcome Measures

Name	Time	Method
Body Mass Index	1 year	BMI will also be calculated.
Waist Circumference	1 year	waist circumference measurement.