Clinico-Anatomical Study of Sira Sharir and Therapeutic Evaluation of Siravedha in management of Giradhrasi(Sciatica)
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Reduction in signs and symptoms of Gridhrasi like Ruk (PAIN),Stambha(Stiffness),Suptata (Numbness)Toda (Pricking Pain) as specified in ayurvedic and modern text
研究概览
简要总结
Gridhrasi is one of 80 Nanatmaja Vata vyadhis explained in Ayurveda classics. The name itself indicates the change of gait shown by the patients because of extreme pain just like Gridhra -Vulture. This disease not only inflicts pain but also causes difficulty in walking, which is incredibly frustrating to the patient.In modern litrature, it is considered Sciatica which shows the same symptoms as Gridhrasi. Sciatica, a condition of leg pain, along with tingling, numbness or weakness of leg that originates in the lower back & travels through the buttock & down the large sciatic nerve in the back of each leg. Nerve roots compressed in this case mostly are L4 – L5 & S1- S3.One of the satisfactory answers for Gridhrasi was given by Siravedha, which was mentioned by numerous Acharyas, including Charaka, Sushruta, Vagbhatta, Chakradatta, and Yogratnakarawith various sites for Siravedha. However, there is a lack of comprehensive scientific research on the efficacy of Raktamokshana therapy, especially Siravedha for Gridhrasi(Sciatica). A clinico-anatomical study is crucial to bridge this knowledge- gap and provide evidence-based insights into the effectiveness of Siravedha as a treatment modality. This research will inform clinical decision-making and contribute to the development of targeted and effective treatment strategies.This study will include 60 patients of Gridhrasi .This will be a nonrandomized single arm trial. Selection will be carried out according to relevant history, sign, symptoms including laboratory investigations and the patients giving written informed consent to participate in the clinical trial. Minimum two sittings of Siravyadha will be conducted on all patients during study. Observations will be recorded on 1st day Before treatment, on 16thday, 31stand on 45th day after treatment. Amount of blood letting will be 20-50ml. Location will be medial side of ankle joint as described in charka samhita. Poorva and pashchat karma will also applicable accordingly. Total duration of treatment can be up to 45 days.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •1.Patients having symptoms of Gridhrasi (Sciatica) according to Ayurvedic classics as well as modern science.
- •2.Patients irrespective of sex, religion, occupation will be selected for study.
- •3.Patient who is willing to take Siravydha Chikitsa.
- •4.Patients fit for Siravyadha & willing to give written informed consent.
排除标准
- •1 Patients below the age of 20 years and above the age of 60 years.
- •2 Patients with co-morbidities/major illness like DM, HTN, Cardiac diseases, TB spine & bones etc 3 Patients with haematological/bleeding disorders, Ca of lumbosacral plexus, Ca of Cauda equine etc.
- •4 Patients who are contraindicated for Siravedha.
- •5 Pregnancy.
- •6 Use of other alternative medication during Ayurvedic treatment.
结局指标
主要结局
Reduction in signs and symptoms of Gridhrasi like Ruk (PAIN),Stambha(Stiffness),Suptata (Numbness)Toda (Pricking Pain) as specified in ayurvedic and modern text
时间窗: 3 months
次要结局
- Improvement in the quality of life & wellbeing.
研究者
Dr Komal Sharma
Dr Sarvepalli Radhakrishnan Rajasthan Ayurved University,Jodhpur
