Evaluation of Regional Distribution of Ventilation in Spontaneous Breathing Patients During Labor With or Without Epidural Analgesia Using EIT (Electrical Impedance Tomography)
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Better lung function after labor with epidural analgesia
研究概览
简要总结
With an efficient epidural analgesia the physiological effects of pain are disabled during labor. Pain may cause an increase of minute volume, oxygen consumption and a decrease of paCO2 (Arterial CO2 pressure). The study will evaluate the lung function before and after labor with and without epidural analgesia. With more efficient breathing, the occurence of atelectasis should be reduced; this effect will be investigated in these settings for the first time with the electrical impedance tomography, which is a completely non-invasive measure.
详细描述
The bedside efficacy of the electrical impedance tomography (EIT) in intensive care settings during mechanical ventilation is known. However, no studies demonstrate its utility during epidural analgesia for labor.
The purpose of this study is to evaluate lung function and atelectasis in pregnant women with or without epidural analgesia, during labor and after delivery.
Only adult consenting patients ASA I & ASA II (American Society of Anaesthesiologists) are included in the study. According to institutional protocols lumbal epidural catheter is inserted and tested at the start of the labor, while patients' parameters are monitored.
Refusal to epidural analgesia, technical difficulties to insert the epidural catheter or any medical contraindication will result in inclusion of these patients in the control group.
Measurement with EIT is not invasive and harmful neither for the mother nor for the child.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Caesarian
- •< 18 years
- •Expulsions
研究组 & 干预措施
Epidural analgesia Ropivacaine
Placement of an epidural catheter to achieve pain relief
干预措施: Epidural analgesia Ropivacaine (Drug)
Epidural analgesia Ropivacaine
Placement of an epidural catheter to achieve pain relief
干预措施: Absence of epidural analgesia (Drug)
Absence of epidural analgesia
No placement of an epidural catheter either because of patient refusal or contraindication
干预措施: Epidural analgesia Ropivacaine (Drug)
Absence of epidural analgesia
No placement of an epidural catheter either because of patient refusal or contraindication
干预措施: Absence of epidural analgesia (Drug)
结局指标
主要结局
Better lung function after labor with epidural analgesia
时间窗: 24h
Using EIT we will map the degree of atelectasis
次要结局
未报告次要终点
研究者
Veerle Van Mossevelde
Data Nurse
Universitair Ziekenhuis Brussel