Comprehensive evaluation of coronary arterial dysfunction using peripheral vascular dysfunction and 3D PET/CT
Not Applicable
Recruiting
- Conditions
- Coronary artery disease, Chronic kidney, disease, Hypertension, Diabetes mellitus
- Registration Number
- JPRN-UMIN000014637
- Lead Sponsor
- Hokkaido University Graduate School of Medicine,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 65
Inclusion Criteria
Not provided
Exclusion Criteria
1.Advanced AV block 2.Bronchial asthma 3.Pregnant women 4.Subjects who will not be able to obtain written informed concent. 5.Others who physicians will consider the contraindication for the participation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The association between brachial artery diameter ,FMD measured by ultrasound, and MBF (myocardial Blood Flow) at rest, ATP(adenosinetriphosphate) stress and, CPT (Cold Pressor Test) stress. CFR(coronary flow reserve), CPT response evaluated by 3D PET/CT will also be compared to FMD and NTG response.
- Secondary Outcome Measures
Name Time Method The association between vascular elasticity,brachial arterial diameter measured by automated oscillometric method and brachial diameters and artery function measured by brachial artery ultrasound.