Enhanced Community First Responder System Evaluation in Singapore

Not Applicable

• Conditions: Out-Of-Hospital Cardiac Arrest
• Interventions: Device: CPRCard Only; Device: CPRCard + TCPR Link App and Web

• Registration Number: NCT06530433
• Lead Sponsor: Singapore General Hospital

Brief Summary

The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR). Despite many lay responders performing CPR, survival rates with good neurological outcomes have not significantly improved, prompting research into the quality of CPR as a critical factor. The study by Gallagher EJ et al. showed a significant survival improvement with high-quality CPR.

To address this, the Unit of Pre-hospital and Emergency Research (UPEC) trained thousands of community first responders (CFRs) in simplified CPR techniques using hands-only and DA-CPR methods. A significant innovation is the CPRcard®, developed by Laerdal in Norway, which offers real-time feedback on the quality of chest compressions. However, only 36% of CFRs using the CPRcard® achieved the desired compression standards, indicating room for improvement.

The study proposes enhancing CFR support with information communication technology (ICT), enabling two-way audio and one-way video communication between CFRs and dispatchers. This aims to reduce stress among responders, increase their willingness to engage with OHCA alerts, and improve CPR quality.

The clinical trial in Singapore will compare the current system against the enhanced CFR support system (eCSS), focusing on the real-time relay of CPR performance data, communication ease, and implementation factors. The high-quality CFR and OHCA registries in Singapore provide a robust setting for this research, aiming to enhance CPR delivery and improve OHCA outcomes through technology and real-time support.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-07
• Study First Submitted: 2024-07-24
• Study First Submitted QC: 2024-07-26
• Study First Posted: 2024-07-31
• Study Start: 2024-08-01
• Last Update Submitted: 2025-05-04
• Last Update Posted: 2025-05-07
• Primary Completion: 2027-07-31
• Study Completion: 2028-12-31

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 165

Inclusion Criteria

• 18 years old and above
• SCDF registered CFRs
• Trial dispatchers with an active account of myResponder® app on their mobile phones

Exclusion Criteria

• The CFRs who are pregnant
• Experiencing any serious physical Conditions
• Mental Health Conditions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
SoC	CPRCard Only	Standard of Care
eCSS	CPRCard + TCPR Link App and Web	enhanced CFR support system (eCSS)

Primary Outcome Measures

Name	Time	Method
Good Chest Compression Depth (4-6cm)	Throughout chest compression before handing over to EMS (up to 24 hours)	OHCA events achieving great proportions of adequate compressions (achieving depth within the target range of 4-6 cm)

Secondary Outcome Measures

Name	Time	Method
Survivor discharging rate	Throughout Hospital Admission (up to 1 year)	Return of spontaneous circulation (ROSC) at scene or at emergency department; survival to discharge; neurologically intact survival

Trial Locations

Locations (1)

Duke-NUS Medical School; 🇸🇬 Singapore, Sigapore, Singapore