A Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose FLuoride toothpaste in preventing and treating dEntal Caries in high-risk older adulTs (REFLECT trial) - REFLECT

Manchester University NHS Foundation Trust0 sites1,174 target enrollmentNovember 27, 2017

Overview

No summary available.

Registry

who.int

Start Date

November 27, 2017

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional clinical trial of medicinal product

Sponsor

•aged 50 years or older
•with a diagnosis of active coronal caries (into dentine) in the last 12 months which may\\may not have been treated, or any root caries; and\\or other risk factors as determined by their GDP.
•receive their dental care in part or fully as an NHS patient
•living in any residential setting, and
•for whom their GDP decides prescription of high concentration fluoride toothpaste is appropriate for the patient
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1\.2 Adults (18\-64 years) yes
•F.1\.2\.1 Number of subjects for this age range 587
•F.1\.3 Elderly (\>\=65 years) yes

•are currently prescribed (by General Dental Practice or General Practitioner) high concentration fluoride toothpaste (for GDPs prescription must have been issued at last examination visit)
•hypersensitivity for Sodium Fluoride and\\or other ingredients used in 5000ppm toothpaste
•are living in the same household as someone already recruited to Reflect
•are unable to provide informed consent