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临床试验/NCT03731065
NCT03731065已完成不适用

Examining Exogenous Carbohydrate Oxidation From Glucose, Multiple Transportable Carbohydrates and Hydrogel Carbohydrate Drinks During Endurance Running

University of Bath1 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2018年10月14日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
9
试验地点
1
主要终点
Peak exogenous carbohydrate oxidation rate

研究概览

简要总结

The aim of this study is to characterise exogenous carbohydrate oxidation rates during exercise, when ingesting glucose (polymers) only, compared to glucose-fructose mixtures, and glucose-fructose mixtures ingested in hydrogel form.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •Maximal oxygen consumption > 50 ml.kg-1.min-1
  • •> 1 year training in endurance running or triathlon
  • •No current injury or injury within the last three months
  • •No history of cardiac or metabolic disease such as coronary heart disease or diabetes
  • •No current or history of gastrointestinal issues
  • •Successful completion of the physical activity readiness questionnaire (PAR-Q)

排除标准

  • •Untrained in endurance running
  • •Current injury or injury within the past three months
  • •History of cardiac or metabolic disease such as coronary heart disease or diabetes
  • •History of or current gastrointestinal issues such as irritable bowel syndrome
  • •Unable to replicate diet and training for 3 and 5 days respectively prior to each experimental visit.

研究组 & 干预措施

Fructose-maltodextrin ingestion

Active Comparator

Ingestion of fructose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

干预措施: Fructose-maltodextrin (Dietary Supplement)

Fructose-maltodextrin hydrogel ingestion

Experimental

Ingestion of fructose and maltodextrin (glucose polymers) encapsulated in alginate-pectin hydrogel, drinks at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

干预措施: Fructose-maltodextrin hydrogel (Dietary Supplement)

Glucose-maltodextrin ingestion

Active Comparator

Ingestion of glucose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

干预措施: Glucose-maltodextrin (Dietary Supplement)

结局指标

主要结局

Peak exogenous carbohydrate oxidation rate

时间窗: 120 minutes

Peak exogenous carbohydrate oxidation rate during 120 min of treadmill running. Measured using isotope ratio mass spectrometry and reported in grams per minute

次要结局

  • Ratings of gastrointestinal discomfort(120 minutes)
  • Total fat oxidation(120 minutes)
  • Plasma lactate concentrations(120 minutes)
  • Heart rate(120 minutes)
  • Plasma glucose concentrations(120 minutes)
  • Plasma non-esterified fatty acid concentrations(120 minutes)
  • Total carbohydrate oxidation(120 minutes)
  • Plasma insulin concentrations(120 minutes)
  • Ratings of perceived exertion(120 minutes)
  • Rate of oxygen consumption(120 minutes)
  • Rate of carbon dioxide production(120 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Javier Gonzalez

Associate Professor

University of Bath

研究点 (1)

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