Clinical studies on the safety and efficacy of platelet rich plasma used in anterior cruciate ligament reconstructio
Phase 1
- Conditions
- rupture of anterior cruciate ligament
- Registration Number
- JPRN-UMIN000014694
- Lead Sponsor
- niversity of tsukuba Department of Orthopaedic Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
Not provided
Exclusion Criteria
History of infection(septic arthritis of the knee, femur / tibia osteomyelitis) / compromised host (Child-Pugh score A-C, diabetes, immunodeficiency, chronic renal failure, cirrhosis of the liver) - autoimmune disease(Various collagen diseases such as rheumatoid arthritis, systemic lupus erythematosus) Anemia (hemoglobin 10 g / dl or less) Blood disease(Coagulation and fibrinolysis abnormalities such as hemophilia) Anticoagulant used (such as aspirin, warfarin) Patients with a suspected history of malignancy within 5 years prior to the date of consent Patients who study physician determines that it is not suitable as a target
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The presence or absence of adverse events in the follow-up period and at the time of surgery 1.Change in the vital signs when it is inserted into the intra-articular ligament with PRP 2.Joint fluid culture of postoperative drain effluent 3.Swelling of knee joint during follow-up times 4.Infection sign during 2weeks
- Secondary Outcome Measures
Name Time Method