Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification With Swept-Source Optical Coherence Tomography

• Conditions: Anterior Chamber Parameters; Phacoemulsification; Anterior Segment Swept-source Optical Coherence Tomography
• Interventions: Procedure: cataract surgery

• Registration Number: NCT03779542
• Lead Sponsor: Yune Zhao

Brief Summary

To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT).To observe the 60 eyes of 60 patients in our study.

Detailed Description

This is a prospective case-control study; 60 eyes of 60 patients who underwent cataract surgery. Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes are classified into two groups, shallow anterior chamber group (30 eyes) and narrow anterior chamber group (30 eyes). AS-SS-OCT was used to measure ACD and angle parameters (angle opening distance(AOD), angle recess area(ARA), trabecular iris space area（TISA）, and trabecular iris angle (TIA). Serial changes in each group were measured before and 3 months after phacoemulsification and IOL, and the differences between the two groups were compared.

Study Timeline

• Study Start: 2018-01-01
• Primary Completion: 2018-06-30
• Status Verified: 2018-12
• Study First Submitted: 2018-12-17
• Study First Submitted QC: 2018-12-17
• Last Update Submitted: 2018-12-17
• Study First Posted: 2018-12-19
• Last Update Posted: 2018-12-19
• Study Completion: 2019-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

patients who underwent cataract surgery -

Exclusion Criteria

patients with mild cataracts do not require surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
open-angle group	cataract surgery	ACD \> 2.68 measured by the swept source AS-OCT and angle \> Shaffer 2 in four quadrants under gonioscope
narrow-angle group	cataract surgery	ACD≤2.68 measured by the swept source AS-OCT and angle≤Shaffer 2 in four quadrants under gonioscope

Primary Outcome Measures

Name	Time	Method
anterior chamber depth	1 year

Trial Locations

Locations (1)

Eye Hospital of Wenzhou Medical College; 🇨🇳 Wenzhou, Zhejiang, China