Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain

Not Applicable

Not yet recruiting

• Conditions: Chronic Low Back Pain (CLBP)

• Registration Number: NCT06963658
• Lead Sponsor: Taif University

Brief Summary

Randomized control trial to examine the immediate effect of isometric exercise on pressure pain threshold (PPT) in adults with chronic low back pain. The secondary aim of this study was to investigate the acute effects of isometric exercise on clinical pain intensity.

Detailed Description

Participants will attend a single visit to the hospital for two hours, which will include collecting demographic details and clinical characteristics through self-reported assessment scales. After that, outcome measures (pain sensitivity and current low back pain intensity) were collected prior to the intervention and repeated immediately post-intervention.

Study Timeline

• Study First Submitted: 2025-03-13
• Status Verified: 2025-05
• Study First Submitted QC: 2025-05-06
• Last Update Submitted: 2025-05-06
• Study First Posted: 2025-05-09
• Last Update Posted: 2025-05-09
• Study Start: 2025-07-01
• Primary Completion: 2025-10-01
• Study Completion: 2026-01-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The primary outcome is pain sensitivity	pre- and immediately post-intervention	Pain sensitivity was assessed via pressure pain threshold (PPT) using a standard procedure. The PPT was assessed by a digital pressure algometer (Wagner digital force Ten FDX 25 with 1 cm 2 rubber tip).This instrument has been widely utilized in various studies and has been shown to be valid and reliable in assessing PPT among people with musculoskeletal pain. If post intervention PPT was higher than pre-intervention value, this indicated that pain sensitivity decreased, suggesting exercise induced hypoalgesia occurred. If post-intervention PPT was lower than pre-intervention PPT, this indicates that pain sensitivity increased, suggesting that exercise induced hyperalgesia occurred.

Secondary Outcome Measures

Name	Time	Method
The secondary outcome is the pain intensity in the lower back	pre- and immediately post-intervention	It is a subjective rating of pain intensity in the lower back using a visual analog scale,where a rating of zero indicates that participant don't have pain and a rating of 10 indicates that the most severe pain. The VAS is reliable and valid for measuring pain in individuals with chronic musculoskeletal conditions. A change of one point in pain intensity on this scale is regarded as the minimal clinically important difference.

Trial Locations

Locations (1)

King Abdullah Hospital in bisha; 🇸🇦 Bisha, Assser, Saudi Arabia