IRCT2016071915536N3已完成未知
The clinical trial of effects of nanocurcumin supplementation on blood nesfatin, insulin resistance indexes, lipids and inflammatory factors in overweight and obese patients with non-alcoholic fatty liver disease ??(NAFLD)?
Vice chancellor for research, Tehran University of Medical Sciences0 个研究点目标入组 84 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 84
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 25 years 至 50 years（—）
- 性别
- All
入选标准
- •Inclusion Criteria:? Non-alcohilic fatty liver disease diagnosed by a radiologist and hepatologist using ?ultrasonography into one of three categories (mild, moderate or severe degree); Age 25–50 years; Overwight or obesity (25=BMI<35).
排除标准
- •? History of alcohol consumption at the time of the study or in the past 12 months, based on ?patient confession; Diagnosed pathological conditions affecting the liver such as viral hepatitis, acute or chronic ?liver failure, cholestasis, liver transplantation, habitual abuse of nonsteroidal anti-inflammatory ?drugs, antibiotics, anti-secretory drugs cause achlorhydria within 3 months before the study, ?Corticosteroids, amiodarone, valproate, prednisone, tamoxifen, perhexiline and methotrexate, ?rapid weight loss, diabetes, heart failure, thyroid disorders, kidney disease, respiratory failure, ?psychological disorders, hereditary hemochromatosis and Wilson disease, alpha-1 antitrypsin ?deficiency, autoimmune diseases, celiac disease, use of liver fat inducer and hormonal drugs; Acute systemic disease, cystic fibrosis disease, muscular dystrophy, protein malnutrition, ?history of gastrointestinal surgery, neurological disorders, structural abnormalities of the ?gastrointestinal tract; The secondary causes of NAFLD, including drugs, surgical procedures, environmental toxins ?and total parenteral nutrition (TPN)?; Conditions lead to the physical inactivity (disability)?; Uncontrolled hypertension (>90/140 mmHg)?; Any diagnosed malignancy; Breast-feeding, pregnancy and or plan for pregnancy in the next 3 months; Professional athlete or regular exercise; Treatment with statins, antihypertensive and ursodeoxy colic acid, probiotics and ?multivitamin-mineral and antioxidant supplements during the three months prior to the ?intervention; Surgery for weight loss in the last year and weight loss program for the past three month; Taking a multivitamin-mineral and or antioxidants supplement at least once a week during the ?study; Not taking more than 10% of prescription supplements?
研究者
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