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Tele-group Cognitive Behavioural Family Intervention for Individuals With Schizophrenia and Their Families

Not Applicable
Not yet recruiting
Conditions
Schizophrenia and Related Disorders
Registration Number
NCT07121166
Lead Sponsor
The Hong Kong Polytechnic University
Brief Summary

This mixed-method study comprises a RCT with a twelve-week post-intervention follow-up and focus group interviews. The RCT study aims to examine the effectiveness of delivering the tgCBFI programme to dyads of people with schizophrenia and their family caregivers, while the focus group interviews aim to qualitatively study the benefits of the tgCBFI programme from the service users and their family caregivers to provide a more in-depth understanding and complement the quantitative data. The main questions it aims to answer are:

Does this online tgCBFI programme reduce the expressed emotion experienced and positive and negative symptoms of individuals with schizophrenia? Does this online tgCBFI programme reduce the perceived care burden and level of mood disturbances of family caregivers?

Detailed Description

Recent network meta-analyses revealed that family interventions were superior to other psychosocial interventions in relapse prevention of people with schizophrenia. The current approaches to family intervention for schizophrenia are to provide support and offer psychoeducation and skill training for family caregivers, such as family psychoeducation and mutual support groups, and work with the whole family, stressing family structure, interaction, and dynamics, such as systemic therapy. Our previous meta-analysis revealed that familial expressed emotion (EE), particularly critical comments, is a robust predictor of schizophrenic relapse, and it is one of the therapeutic foci of the family intervention to benefit the recovery of service users with schizophrenia. A proposed cognitive model of caregiving suggested that cognitive reappraisal, including reattribution of self-control on caregiving and reattribution of service users' control on illness progression, is one of the recommended therapeutic components to assist family caregivers in relieving their mood disturbances as well as negative expressed emotion. A framework of cognitive behavioural therapy (CBT) for service users with psychosis and their family caregivers has also been suggested to improve the clinical outcomes of the service users and extend the individual CBT to the family group. Built upon these two mainstream approaches of behavioural and structural family interventions, cognitive behavioural family intervention (CBFI) focuses on cognitive appraisals in family relationships between service users and their families, aligning with the proposed cognitive model of caregiving in resolving the two negative attrition-emotion pathways. Our previous meta-analysis indicates that CBFI is superior to treatment as usual (TAU) in reducing the severity of positive and negative symptoms of people with schizophrenia immediately following the intervention. Recent systematic reviews supported that telepsychiatry/telehealth is a feasible and acceptable approach for people with severe mental illness and their family caregivers. This tgCBFI programme is a brief, novel group CBT-based family intervention using a telehealth delivery mode (i.e., via Zoom) to care for people with schizophrenia and their family caregivers in the community.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
200
Inclusion Criteria
  • current diagnosis of schizophrenia-spectrum disorders, based on ICD-10 made by the treating clinicians,
  • aged 18-64, and
  • able to read and write Chinese
Exclusion Criteria
  • having co-morbidity of learning disability, organic/neurological conditions, or substance use disorder, and
  • living in a hostel

II. Family caregivers

Inclusion Criteria:

  • aged 18 or above,
  • able to read and write Chinese,
  • live with service users, and
  • nominated by the service users

Exclusion Criteria:

  • having active psychiatric conditions

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Expressed emotion experienced by the service users as assessed by the Concise Chinese Level of Expressed Emotion Scale (CCLEES)From enrollment to twelve-week post-intervention follow-up

It has twelve items using a four-point Likert scale with three subscales. The total score ranges from 12 to 48, and a higher score indicates a higher level of familial expressed emotion.

Secondary Outcome Measures
NameTimeMethod
Positive and negative symptoms of service users as assessed by the Positive and Negative Syndrome Scale (PANSS)From enrollment to twelve-week post-intervention follow-up

It has thirty items using a seven-point Likert scale with three subscales. The subscale scores of positive and negative symptoms range from 7 to 49, while that of general psychopathology ranges from 16 to 112. A higher score indicates a higher level of severity of psychiatric symptoms.

Perceived care burden of family caregivers as assessed by the Family Burden Interview Schedule (FBIS)From enrollment to twelve-week post-intervention follow-up

It has 25 items using a three-point Likert scale with six subscales. The total score ranges from 0 to 50. A higher score indicates a higher level of perceived family care burden.

Mood disturbances of family caregivers as assessed by the Hospital Anxiety and Depression Scale (HADS)From enrollment to twelve-week post-intervention follow-up

It comprises fourteen items using a four-point Likert scale with two subscales. The subscale scores of depression and anxiety range from 0 to 21. A higher score indicates a higher level of mood disturbance.

Service satisfaction of participants from the tgCBFI group as assessed by the Client Satisfaction Questionnaire (CSQ-8)within one week after the intervention

It consists of eight items using a four-point Likert scale. The total score ranges from 8 to 32. A higher score indicates a higher level of service satisfaction.

Qualitative feedback from the participants in the tgCBFI group as assessed by focus group interviewswithin one month after the intervention

For each interview, a group of eight participants will be interviewed for up to 45 minutes

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