ACTRN12612000650897已完成2 期
A double-blind, placebo-controlled cross-over study of the effect of corticosteroids on sleep quality- a pilot study in patients with advanced cancer
Mater Misericordiae Health Services Brisbane Ltd0 个研究点目标入组 53 人开始时间: 2012年6月19日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 53
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •a diagnosis of cancer
- •-on a stable dose of corticosteroid (CS) for the previous 48hours for any indication
- •-likely to remain on a stable dose of CS for the next 10 days
- •-patients on another CS other than dexamethasone must be prepared to convert to an equivalent dose of dexamethasone
- •- likely to remain on a stable doses of sedatives, hypnotics and analgesics throughout study period.
- •- likely to remain at home or in hospital (ie in a stable environment) for the duration of the study period
- •- life expectancy> 1 month
- •- able to swallow tablets
- •- ability to understand the patient information sheet, sign a fully informed consent and comply with trial requirements
排除标准
- •-patients prescribed dexamethasone for emergency management, eg. spinal cord compression, superior vena cava syndrome, raised intracranial pressure (ICP)
- •-patients being weaned off steroids not willing to remain on a stable dose for 1 0 days
- •-a history of psychosis
- •-concurrent medication likely to cause insomnia eg psychostimulants
- •-uncontrolled diabetes mellitus
研究者
相似试验
进行中（未招募）
1 期
A study to assess the efficacy of a vitamin D-containing ointment applied on the skin to improve wound healing in butterfly childreEUCTR2016-001967-35-ATniversitätsklinik für Dermatologie, Paracelsus medizinische Privatuniversität Salzburg15
终止
4 期
Treatment of disordered blood pressure in spinal cord injuryHypotensionSpinal cord injuryACTRN12613001021763Austin Hospital4
进行中（未招募）
不适用
A placebo-controlled, double-blind, cross-over study with rupatadine 10 mg in 30 mosquito-bite allergic adult subjectsRupatadiini-antihistamiini hyttyspistoallergiassa - Rupatadiini-antihistamiini hyttyspistoallergiassamosquito-bite allergic adultsEUCTR2005-004422-50-FIJ.Uriach y Compania S.A.,30
已完成
不适用
A placebo-controlled, single-blind, crossover study to assess the effects of New Zealand pine bark extract (Enzogenol®) on glycaemic responses in healthy participantsDysglycaemiaGlycaemic controlDiet and Nutrition - Other diet and nutrition disordersMetabolic and Endocrine - DiabetesDiabetesACTRN12619001571167Massey University25
进行中（未招募）
1 期
A double-blind placebo-controlled cross-over study to determine if melatonin can improve the length of day time sleep in subjects with transient misalignment of the sleep-wake cycle as a result of working permanent night shifts.Transient misalignment of the sleep-wake cycle as a result of working night shifts (insomnia in night shift workers)EUCTR2005-000120-17-GBAlliance Pharmaceuticals Ltd60