The Mechanism and Prognosis of Pulmonary Circulation Dysfunction
- Conditions
- VTE
- Registration Number
- NCT03616366
- Lead Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
- Brief Summary
Venous thromboembolism (VTE) is a condition which influenced by both environmental and genetic factors. This study is going to explore new significant Single nucleotide polymorphisms (SNPs) associated with VTE by Genome-Wide Association Studies (GWAS) and bioinformatics analysis. Transcriptomics and cytokine antibody array are also used to find new biomarkers of VTE's early diagnosis, severity and prognosis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
- Chinese Han population older than 14 years old
- Acute VTE patients diagnosed in 1 month
- With informed consent
Exclusion Criteria
- Patients with psychosis
- Patients with contraindications for computed tomographic pulmonary angiography (CTPA)
- Chronic VTE
- Recurrence of chronic VTE
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All cause death 6 months death
- Secondary Outcome Measures
Name Time Method Venous thromboembolism (VTE) recurrence 6months VTE recurrence detected by echocardiography or CTPA scan
chronic thromboembolism pulmonary hypertension(CTEPH) 6 months newly developed CTEPH detected by pulmonary angiography
Trial Locations
- Locations (1)
Cardiovascular Institute and Fu Wai Hospital
🇨🇳Beijing, Beijing, China