Safety of low dose Ramipril in voluntary kidney donors after donation.
Not Applicable
- Registration Number
- CTRI/2022/01/039109
- Lead Sponsor
- Department of Nephrology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) age 18 to 60 years
Exclusion Criteria
1) diagnosis of hypertension
2) history of allergy to ACE inhibitors
3) History of angioedema
4) history of allergy to iodinated contrast media
5) systolic BP < 100mm Hg
6)Planning pregnancy in next 9 months after renal donation (females)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate safety of low dose ACEi (Ramipril 1.25mg) in living kidney donors.Timepoint: 6 months
- Secondary Outcome Measures
Name Time Method To ascertain change in measured GFR in living donors at 6 months after kidney donation by plasma clearance of IohexolTimepoint: 6 months;To ascertain change in vascular stiffness in living donors at 6 months after kidney donation by PWVTimepoint: 6 months