What is an Important Change in the Short Physical Performance Battery (SPPB)?

Completed

• Conditions: Respiratory Tract Diseases; Lung Diseases
• Interventions: Other: Pulmonary rehabilitation

• Registration Number: NCT01649193
• Lead Sponsor: Royal Brompton & Harefield NHS Foundation Trust

Brief Summary

The purpose of this study is to determine the important change in the Short Physical Performance Battery (SPPB) when used in patients with lung disease. The SPPB is a simple physical test that measures balance and the functioning of the legs. It has been widely used in healthy elderly populations and predicts hospital admission and the onset of disability. The SPPB has not previously been used in patients with lung disease, and it is not clear what change in this test is considered meaningful and worthwhile by patients or doctors (the minimal clinically important difference: MID). Knowing what the MID for the SPPB will allow researchers and doctors to evaluate the effectiveness of current and new treatments, and to detect improvement or deterioration in the condition of patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03
• Study First Submitted: 2012-07-09
• Study First Submitted QC: 2012-07-20
• Study First Posted: 2012-07-25
• Primary Completion: 2014-02
• Study Completion: 2014-05
• Status Verified: 2014-11
• Last Update Submitted: 2014-11-04
• Last Update Posted: 2014-11-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• All patients entering pulmonary rehabilitation

Exclusion Criteria

• Any patient in whom mobility and lower limb function have been significantly affected by a neuromuscular cause, severe peripheral vascular disease or amputation.
• Any patient whom the chief investigator feels it is unsafe to exercise (e.g. unstable cardiac disease).

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Chronic Respiratory Disease	Pulmonary rehabilitation	Any patient with a chronic respiratory disease referred for pulmonary rehabilitation

Primary Outcome Measures

Name	Time	Method
Change from baseline of Short Physical Performance Battery	8 weeks

Secondary Outcome Measures

Name	Time	Method
Anchor question (5-point Likert scale)	8 weeks
Change from baseline of MRC Dyspnoea Scale	8 weeks
Change from baseline of St George's Respiratory Questionaire	8 weeks

Trial Locations

Locations (1)

Harefield Hospital; 🇬🇧 Harefield, Middlesex, United Kingdom