Determining the Minimal Important Difference of the Short Physical Performance Battery and 4m Gait Speed in Chronic Respiratory Disease Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Change from baseline of Short Physical Performance Battery
研究概览
简要总结
The purpose of this study is to determine the important change in the Short Physical Performance Battery (SPPB) when used in patients with lung disease. The SPPB is a simple physical test that measures balance and the functioning of the legs. It has been widely used in healthy elderly populations and predicts hospital admission and the onset of disability. The SPPB has not previously been used in patients with lung disease, and it is not clear what change in this test is considered meaningful and worthwhile by patients or doctors (the minimal clinically important difference: MID). Knowing what the MID for the SPPB will allow researchers and doctors to evaluate the effectiveness of current and new treatments, and to detect improvement or deterioration in the condition of patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients entering pulmonary rehabilitation
排除标准
- •Any patient in whom mobility and lower limb function have been significantly affected by a neuromuscular cause, severe peripheral vascular disease or amputation.
- •Any patient whom the chief investigator feels it is unsafe to exercise (e.g. unstable cardiac disease).
结局指标
主要结局
Change from baseline of Short Physical Performance Battery
时间窗: 8 weeks
次要结局
- Anchor question (5-point Likert scale)(8 weeks)
- Change from baseline of MRC Dyspnoea Scale(8 weeks)
- Change from baseline of St George's Respiratory Questionaire(8 weeks)