TCTR20180302007已完成未知
A randomized controlled trial study comparing high- and low-dose vitamin D2 supplementation protocol in patients with osteoporotic hip fractures
/A0 个研究点目标入组 159 人开始时间: 2018年3月2日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 159
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 50 Years 至 0 N/A (No limit)（—）
- 性别
- All
入选标准
- •All patient who admitted to Siriraj Hospital , Mahidol University, Bangkok, Thailand, between July,10 2016 †June, 15 2017. They were invited to participate if they were aged 50 years or over and presenting with a low energy hip fracture, peritrochanteric or neck of femur fracture
排除标准
- •patients who suffered from associated pathological fracture from malignancy or other metabolic bone disease such as paget’s disease, Hyperparathroidism; hypercalcemia (>10.2 mg/dL)[27];
- •history of disease that high risk for altered serum calcium level such as tumor, granulomatous disease;
- •significant renal impairment (GFR ≤ 30 ml/min);
- •liver disease (AST or ALT level >2 times the upper limit of the normal range); undergoing supplement with oral vitamin more than 400 IU daily; undergoing treatment with drug that may altered serum 25(OH)D level such as phenytoin, phenobarbital;
- •history of malabsorbtion disease such as radiation enteritis, inflammatory bowel disease, short bowel syndrome.
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