Lifestyle-Related Health Outcomes in Prediabetes and Diabetes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity
- Sponsor
- Indiana University
- Enrollment
- 78
- Locations
- 1
- Primary Endpoint
- Changes in the oral disposition index measured by oral glucose tolerance test
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
This study looks as how a health education intervention strategy effects health outcomes in overweight and obese adolescents.
Detailed Description
This study aims to do the following: 1. To evaluate whether a health education and coaching strategy in overweight and obese adolescents (≥85th percentile) with high risk for type 2 diabetes is superior to usual care (single nutrition consultation) for weight management, clinical health outcomes (measures of glucose tolerance), lifestyle behavior outcomes (diet and physical activity) and outcomes of importance to patients such as satisfaction with the health care team, treatment goals, and psychosocial functioning. 2. To evaluate whether a health education and coaching strategy in obese adolescents with diabetes (type 1 or type 2) is superior to usual care (single nutrition consultation) for weight management, clinical health outcomes (measures of diabetes control), lifestyle behavior outcomes (diet and physical activity) and outcomes of importance to patients such as satisfaction with the health care team, treatment goals, and psychosocial functioning. 3. At baseline, before the interventions described in Aims 1 and 2, to identify key diet and physical activity factors, patient characteristics, or biomarkers which are predictive of diabetes risk. 4. At baseline, before the interventions described in Aims 1 and 2, can associations between glycemia, cardiometabolic risk factors, and diet and physical activity behaviors in overweight and obese adolescents who are at risk for type 2 diabetes be identified using the Bright Futures questionnaire, a survey for lifestyle behavior which is normally used in the clinic setting.
Investigators
Nana Gletsu Miller
Associate Professor
Indiana University
Eligibility Criteria
Inclusion Criteria
- •male and female adolescents/young adults,
- •Tanner stage II-V,
- •overweight or obese (body mass index ≥85th percentile for age and sex).
Exclusion Criteria
- •use of medications that adversely affect glucose metabolism (such as glucocorticoid-containing medications or atypical antipsychotics), and
- •syndromic obesity (such as Prader Willi, hypothalamic obesity, or Laurence- Moon-Biedl).
Outcomes
Primary Outcomes
Changes in the oral disposition index measured by oral glucose tolerance test
Time Frame: 6 months
oral disposition index = insulinogenic index x 1/fasting insulin