Analysis of the Effectiveness and Safety of Retrograde Intrarenal Surgery (RIRS) Under Local Anesthesia and Its Influencing Factors
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- pain score
研究概览
简要总结
Retrograde intrarenal surgery (RIRS) is a well-established technique and is the first-line treatment option for upper urinary tract stones <2cm. Currently, most ureteroscopic procedures are performed under general or epidural anesthesia, both of which are safe and feasible. In recent years, more and more studies have shown that retrograde intrarenal surgery (RIRS) under local anesthesia is safe and feasible. However, we can see that the current studies on RIRS under local anesthesia are mostly case reports, and there is a lack of systematic studies on the safety and effectiveness of RIRS under local anesthesia and its influencing factors. Therefore, the researchers hope to conduct a single-center prospective observational study to explore the safety, effectiveness and influencing factors of RIRS under local anesthesia, so as to optimize the surgical process of RIRS under local anesthesia, improve the surgical success rate and ensure surgical safety。
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Kidney stones or upper ureteral stones 1-4cm;
- •Age 18-70 years old;
- •American Society of Anesthesiologists(ASA) score Ⅰ, Ⅱ and Ⅲ;
排除标准
- •Surgical operations other than RIRS are required for patients with middle and lower ureteral calculi;
- •There are anatomical abnormalities, such as ureteral stenosis, urine flow diversion, ectopic kidney, horseshoe kidney, duplicate kidney, etc.
- •Severe heart, brain and lung diseases;
结局指标
主要结局
pain score
时间窗: 1 day after sugery
Visual Analogue Scale(VAS),The basic method is to use a moving ruler about 10cm long, with 10 scales on one side and "0" and "10" points on both ends, where 0 represents no pain and 10 represents the most unbearable pain.
Operative time
时间窗: During surgery
Surgery duration, minutes. From the insertion of the guide wire to the end of the indwelling ureteral stent.
次要结局
- stone-free rate(From enrollment to the end of treatment at 24 hours)
- Complication rate(1 month after sugery)
研究者
Guohua Zeng
Ph.D and M.D
The First Affiliated Hospital of Guangzhou Medical University
