Biomarker Identification for Bladder Cancer Patients
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 179
- 试验地点
- 1
- 主要终点
- Identify novel biomarkers for bladder cancer
研究概览
简要总结
To develop a simple blood and urine test that we would perform before patients start their treatment to predict the risk that their bladder cancer might come back. To develop this test the investigators plan to analyze blood, urine and cancer tissue from bladder cancer patients and follow them closely during and after treatment. This will include looking for changes in proteins and genes that might play a role in bladder cancer biology. The investigators will then compare the information obtained from the studies of blood, urine and cancer tissue between patients that are cured and those whose cancer comes back. The knowledge about these differences between patients can then potentially be used to develop a blood or urine test to tell us who has a high risk for having bladder cancer come back.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients ≥18 years old.
- •Patients suspected, clinically diagnosed, or histologically diagnosed bladder cancer.
- •Patients undergoing cystoscopy without cancer suspicion.
- •Ability to give an informed consent.
排除标准
- •Patients receiving concurrent therapy for a second malignancy.
- •< 18 years old.
- •Inability to give an informed consent.
结局指标
主要结局
Identify novel biomarkers for bladder cancer
时间窗: up to 5 years
Predict and detect bladder cancer recurrence, specifically through development of biomarkers using bladder cancer tissue samples as well as blood and urine samples. Detect the recurrence of disease through development of blood and urine biomarkers using pre-therapy and post-therapy biospecimens.
次要结局
未报告次要终点
研究者
Arnab Chakravarti
Principal Investigator
Ohio State University Comprehensive Cancer Center