NCT03702140招募中2 期
Examination How the Administration Period of Teriparatide Affects Bone Metabolism and Bone Mineral Density Prior to Denosumab Therapy
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Bone mineral density
研究概览
简要总结
The aim of this study is to examine the efficacy and adverse events in the following 3 groups in osteoporosis patients:
- The administration period of teriparatide is less than 6 months and thereafter, denosumab for 24 months.
- The administration period of teriparatide is from 6 to 12 months and thereafter, denosumab for 24 months.
- The administration period of teriparatide is more than 12 months and thereafter, denosumab for 24 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Osteoporotic patients who want to take teriparatide and denosumab
排除标准
- •Patients who are allergic to teriparatide or denosumab Patients who are pregnant or breast-feedin
研究组 & 干预措施
TPTD 6M
Active Comparator
干预措施: "Teriparatide", "Forteo® or Teribon" (Drug)
TPTD 6-12M
Active Comparator
干预措施: "Teriparatide", "Forteo® or Teribon" (Drug)
TPTD 12-24M
Active Comparator
干预措施: "Teriparatide", "Forteo® or Teribon" (Drug)
结局指标
主要结局
Bone mineral density
时间窗: Change from Baseline Values at 1 year
次要结局
未报告次要终点
研究者
Yukio Nakamura
Lecturer at Shinshu University School of Medicine
Shinshu University
研究点 (1)
Loading locations...
相似试验
已完成
3 期
Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep ApneaObesityNCT05412004Eli Lilly and Company469
尚未招募
4 期
Efficacy, Metabolism and BMD of the 3-month TP Compared to the 1-month TP in ICPPCentral Precocious PubertyNCT06487143Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University134
已完成
不适用
Prospective Study of TW in the Treatment of LN Type V With Gross ProteinuriaProteinuriaCTXLupus NephritisNCT00935389Nanjing University School of Medicine44
Unknown
不适用
Trip-Tox, Effectiveness of Triptans Before and After Onabotulinumtoxin A Treatment in Chronic MigraineChronic MigraineNCT04871152Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau100
已完成
3 期
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related ComorbiditiesOverweightObesityNCT05822830Eli Lilly and Company751