Multicenter Observational Study of Epidemiology of Cardiovascular Diseases and Risk Factors in Different Regions of Russian Federation
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 18,000
- 试验地点
- 2
- 主要终点
- all cause mortality
研究概览
简要总结
The study addresses epidemiology of cardiovascular risk factors and major cardiovascular diseases in Russian Federation (urban and rural population). 12 regions of 1600 participants in each will be included.
详细描述
Plasma lipids and fasting glucose, heart rate and blood pressure, anthropometry, smoking and alcohol questionaries, nutrition, sleep quality, stress will be assessed. ECG records are obtained form all participants. Subclinical target organ damage (carotid and periferal atherosclerosis, pulse wave velocity) will be measured in selected sites. Brain natriuretic peptide, adipose tissue cytokines, hsCRP and genetic markers are also under evaluation
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 25 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •informed consent
排除标准
- 未提供
结局指标
主要结局
all cause mortality
时间窗: 10 years
all cause motality registered by official statistics
次要结局
- Stroke(10 years)
- Miocardial infarction(10 years)
- Cardiovascular mortality(10 years)
研究者
Conrady Alexandra
professor
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health