Multicenter Observational Study of Epidemiology of Cardiovascular Diseases and Risk Factors in Different Regions of Russian Federation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hypertension
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
- Enrollment
- 18000
- Locations
- 2
- Primary Endpoint
- all cause mortality
- Last Updated
- 9 years ago
Overview
Brief Summary
The study addresses epidemiology of cardiovascular risk factors and major cardiovascular diseases in Russian Federation (urban and rural population). 12 regions of 1600 participants in each will be included.
Detailed Description
Plasma lipids and fasting glucose, heart rate and blood pressure, anthropometry, smoking and alcohol questionaries, nutrition, sleep quality, stress will be assessed. ECG records are obtained form all participants. Subclinical target organ damage (carotid and periferal atherosclerosis, pulse wave velocity) will be measured in selected sites. Brain natriuretic peptide, adipose tissue cytokines, hsCRP and genetic markers are also under evaluation
Investigators
Conrady Alexandra
professor
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Eligibility Criteria
Inclusion Criteria
- •informed consent
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
all cause mortality
Time Frame: 10 years
all cause motality registered by official statistics
Secondary Outcomes
- Stroke(10 years)
- Miocardial infarction(10 years)
- Cardiovascular mortality(10 years)