CGH-array in Prenatal Diagnosis of Isolated Severe and Early Intra-uterine Growth Restriction

• Conditions: IUGR; Prenatal Disorder; Genetic Disease

• Registration Number: NCT04729361
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

According to french recommandations for IUGR management we have to propose a CGH-array analysis if the IUGR is severe (bellow the 3rd percentile) and early (in the second trimester). However there is no data to support this point of view.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-01
• Study First Submitted: 2021-01-25
• Study First Submitted QC: 2021-01-25
• Last Update Submitted: 2021-01-25
• Study First Posted: 2021-01-28
• Last Update Posted: 2021-01-28
• Study Start: 2021-01-31
• Primary Completion: 2021-03-15
• Study Completion: 2021-11-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

• pregnant women
• fetus with an isolated intra-uterine growth restriction (IUGR) severe (bellow the third percentile on CFEF curves) and early (between 21 and 24 gestational weeks).

Exclusion Criteria

• associated IUGR (with other abnormalities during prenatal screening)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rate of abnormal CGH-array in the groupe "severe and early" UGR	one-time (at the time of the analysis)