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A multicentre, randomised, controlled, clinical Investigation of a standalone decision support Algorithm for Neonatal Seizure Recognitio

Completed
Conditions
convulsions
fits
10039911
Registration Number
NL-OMON44340
Lead Sponsor
niversity College Cork, National University of Ireland
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

Neonates 36-44 weeks corrected gestational age in whom EEG monitoring is indicated because they are deemed to be;
- at high risk of seizures,
or
- are experiencing seizures

Exclusion Criteria

No parental/guardian consent

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Diagnostic accuracy of investigation personnel with and without the use of the<br /><br>ANSeR Software System in routine clinical practice for a minimum of 2 hours up<br /><br>to maximum of 100 hours of post-natal EEG monitoring, using an expert panel as<br /><br>the reference standard. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>The following secondary endpoints will be used to determine the impact of the<br /><br>ANSeR Software System.<br /><br>(1) The number and duration of all electrographic seizures will be quantified<br /><br>to measure seizure burden in both groups. Electrographic seizures will be<br /><br>determined by the expert EEG committee.<br /><br>(2) The number of AEDs administered in both groups will be compared. The<br /><br>timing of administration will be correlated with on-going electrographic<br /><br>seizure activity in each group to determine the appropriateness of AED<br /><br>administration</p><br>
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