MedPath

WT1 Peptid Vaccination in Carcinomas

Phase 2
Conditions
WT1 Expressing Carcinoma
Registration Number
NCT00153608
Lead Sponsor
Charite University, Berlin, Germany
Brief Summary

In this trial HLA-A2+ patients with WT1 expressing carcinomas are vaccinated with a peptide from the leukemia associated antigen WT1 together with immunological adjuvants KLH as T-helper protein and GM-CSF

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
25
Inclusion Criteria
  • Metastatic cancer, no standard treatment option
  • Resected cancer with minimal residual disease, no standard treatment option
  • WT-1 expression
  • HLA-A2
Exclusion Criteria
  • Concurrent chemotherapy

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Clinical efficacy
Secondary Outcome Measures
NameTimeMethod
Immune response
Safety

Trial Locations

Locations (1)

Hem&Onc Charité CBF

🇩🇪

Berlin, Germany

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