Perioperative stress response in infants undergoing cardiac surgery: a comparison of three alfentanil dosage regimens
Completed
- Conditions
- Surgery: StressSurgeryOther congenital malformations of heart
- Registration Number
- ISRCTN70255514
- Lead Sponsor
- Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
90 infants aged less than 1 year undergoing palliative or corrective surgery of congenital cardiac defects involving cardiopulmonary bypass.
Exclusion Criteria
Not provided at time of registration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma cortisol concentration 5 min following sternotomy.
- Secondary Outcome Measures
Name Time Method ot provided at time of registration
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms of alfentanil influence perioperative stress response in infants with congenital heart defects?
How does alfentanil compare to standard-of-care opioids in managing stress during pediatric cardiac surgery?
Are there specific biomarkers that predict alfentanil efficacy in infants undergoing heart surgery?
What are the potential adverse events associated with varying alfentanil dosages in neonatal cardiac procedures?
What combination therapies or alternative analgesics are being explored alongside alfentanil for pediatric cardiac surgery outcomes?