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临床试验/NCT04674202
NCT04674202招募中不适用

Pilot Study: Comparison of Patients' Knowledge of Direct Oral Anticoagulants in Post-hospitalization Between 2 Cardiology Departments Offering or Not a Pharmaceutical Interview During Hospitalization

Direction Centrale du Service de Santé des Armées2 个研究点 分布在 1 个国家目标入组 154 人开始时间: 2021年1月18日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
154
试验地点
2
主要终点
Proportion of patients with a "satisfactory" knowledge score 3 months after hospital discharge

研究概览

简要总结

Direct oral anticoagulants (Rivaroxaban, Apixaban and Dabigatran) are an alternative to anti-vitamin K drugs and low molecular weight heparins in many cardiovascular diseases.

This new class of anticoagulants represents a particular and very promising advance: they are administered orally, their mechanism of action is rapid and direct on coagulation and their predictable pharmacological action allows for administration at fixed doses. In contrast to anti-vitamin K, there is no need for routine biological monitoring.

However, their therapeutic range is narrow and there is no routine biological monitoring. Rigorous compliance is therefore necessary. In addition, there are no official validated recommendations either for the measurement of anticoagulant activity in certain emergency situations, or for the management of severe bleeding (except recently for Pradaxa®).

Their correct use requires the training and involvement of health professionals as well as information and support for patients.

Pharmaceutical interviews are one of the main ways in which pharmacists can ensure this security through personalized and optimal patient care.

The purpose of these interviews is to:

  • Reinforce the pharmacist's advisory, educational and preventive roles with patients;
  • To enhance the pharmacist's expertise in the area of medication;
  • To evaluate the patient's knowledge of his or her treatment;
  • To assess the patient's knowledge of his or her treatment; To seek the patient's therapeutic adherence and help him or her to take ownership of his or her treatment;
  • To evaluate, in the long term, the patient's appropriation of his or her treatment.

In this way, they enable involvement with patients while providing a link between healthcare professionals, which is essential for optimal patient care.

In recent years, numerous studies have been conducted on pharmaceutical interviews in the United Kingdom and the Netherlands.

On the other hand, few studies have been conducted in France to evaluate the clinical impact of pharmaceutical interviewing in medical services.

The aim of this study is to compare patients' knowledge of direct oral anticoagulants between 2 cardiology departments offering or not a pharmaceutical interview.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient hospitalized for more than 48 hours in a cardiology department with a discharge prescription for curative anticoagulation.
  • Indication for a direct oral anticoagulant for atrial fibrillation, deep vein thrombosis or pulmonary embolism

排除标准

  • Patients treated for the prevention of venous thromboembolic disease who have undergone scheduled total hip replacement or total knee replacement surgery.
  • Patient with cognitive impairment
  • Patients with a previous prescription for a direct oral anticoagulant

结局指标

主要结局

Proportion of patients with a "satisfactory" knowledge score 3 months after hospital discharge

时间窗: 3 months after hospital discharge

Knowledge of direct oral anticoagulants will be assessed with a 4 item questionnaire. The score ranges from 0 "no knowledge" to ≥ 3 "satisfactory knowledge".

次要结局

未报告次要终点

研究者

发起方
Direction Centrale du Service de Santé des Armées
申办方类型
Other
责任方
Sponsor

研究点 (2)

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