A randomised controlled trial to assess whether the amount of mesentery removed, or the type of bowel join used during surgery for Crohn's disease, can affect the chances of getting further disease
- Conditions
- Crohn’s diseaseDigestive SystemCrohn disease [regional enteritis]
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 308
People aged over 18 years undergoing ileocaecal resection for primary/recurrent Crohn’s disease where an anastomosis is carried out
Participant exclusion criteria as of 10/11/2023:
1. Patients with markedly extensive inflammation affecting the vascular root of the mesentery seen on imaging or at operation
2. Patients undergoing stoma formation proximal to the anastomosis
3. Patients who have a contraindication to subsequent colonoscopy
4. Patients unable to give full informed consent
5. Patients who are pregnant (as ascertained by standard pregnancy tests undertaken at preoperative visits as per standard clinical care)
6. Patients who, in the opinion of the principal investigator, do not meet the criteria for relevant surgery
Previous participant exclusion criteria:
1. Patients with markedly extensive inflammation affecting the vascular root of the mesentery seen on imaging or at operation
2. Patients undergoing stoma formation
3. Patients who have a contraindication to subsequent colonoscopy
4. Patients unable to give full informed consent
5. Patients who are pregnant (as ascertained by standard pregnancy tests undertaken at preoperative visits as per standard clinical care)
6. Patients who, in the opinion of the principal investigator, do not meet the criteria for relevant surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method