CTRI/2022/03/041539尚未招募不适用
Study on levels of the Th17 and Treg pathway cytokines in Type 1 leprosy reactions
ABVIMS and Dr RML Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2022年8月4日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Levels of cytokine of Th 17 and Treg pathway in skin and blood of patients presenting with Type 1 leprosy reactions
研究概览
简要总结
To measure the levels of cytokines of Th17 and Treg pathway in skin and blood of patients presenting with type 1 leprosy reactions.
To compare with levels in non reactional leprosy patients
To reassess the levels of the cytokines following resolution of the reaction
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Adult Patients of either sex with Untreated recent Type 1 leprosy reaction, irrespective of MDT status 2.Presence of skin signs of Type 1 Leprosy reaction, with or without neuritis/ nerve function impairment.
排除标准
- •Those already on treatment for Type 1 reaction <18 Years of age Immunosuppressed patients- by way of disease or drugs Pregnancy and lactating females Presence of any other chronic illness.
结局指标
主要结局
Levels of cytokine of Th 17 and Treg pathway in skin and blood of patients presenting with Type 1 leprosy reactions
时间窗: Baeline and after resolution of reaction
次要结局
- To measure levels of cytokines of Th17 and Treg pathway in non reactional leprosy patients(Baseline)
研究者
研究点 (1)
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