Magnesium sulphate for the treatment of pre-eclampsia: a trial to evaluate the effects on women and babies

Medical Research Council (MRC) (UK)0 个研究点目标入组 10,141 人开始时间: 2000年10月25日最近更新: 2015年1月13日

适应症

试验速览

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•1. Not delivered, or delivered within the last 24 hours
•2. Blood pressure today is =90 mmHg diastolic or =140 mmHg systolic, on at least two occasions
•3. Proteinuria of at least 1+
•4. There is clinical uncertainty about whether magnesium sulphate would be beneficial (factors likely to influence this uncertainty are the presence of any of the following: hypereflexia, frontal headache, abnormal liver function or coagulation, and epigastric tenderness)

•The woman does not wish to be randomised, for whatever reason/the attending clinician believes magnesium sulphate should either be given or withheld/hypersensitivity to magnesium/renal failure (women who have renal impairment may be randomised, but the volume of allocated treatment should be halved for each dose)/hepatic coma if risk of renal failure/myaesthenia gravis.

发起方

Medical Research Council (MRC) (UK)