Chronic Alcohol and Brain Stress Circuit Response

Completed

• Conditions: Stress; Alcoholism

• Registration Number: NCT01031264
• Lead Sponsor: Yale University

Brief Summary

Alcoholism is among the top three causes of preventable death and disease in the US (Mokdad et al., 2004; Room et al., 2005). Stress plays an important role in the development of alcoholism and in high vulnerability to alcohol relapse. This study will provide a greater understanding of the mechanism by which stress and alcohol consumption interacts to influence development of compulsive alcohol seeking and vulnerability to stress-induced drinking, and the results will have significant implications for the development of new prevention and treatment interventions for alcoholism.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2009-01
• Study First Submitted: 2009-12-10
• Study First Submitted QC: 2009-12-11
• Study First Posted: 2009-12-14
• Primary Completion: 2014-12
• Study Completion: 2014-12
• Status Verified: 2015-07
• Last Update Submitted: 2015-07-28
• Last Update Posted: 2015-07-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• ages 21-50

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assess differences in reactivity to cue imagery	2 years from start of study	Physiological measures will be collected (heart rate, blood levels), self-reports of emotional states completed \& alcohol taste task performed

Trial Locations

Locations (1)

Yale Stress Center; 🇺🇸 New Haven, Connecticut, United States